UCI
School of Biological Sciences
Developmental and Cell Biology

Peter Bryant

Peter Bryant, PhD

Peter Bryant, Ph.D.
Professor

4221 McGaugh Hall
University of California Irvine
Irvine, CA 92697

Tel: (949) 824-4714
Fax: (949) 824-3571
Email: pjbryant@uci.edu
Website: Lab Homepage

Cancer genetics - The objective of my research is to understand how cell proliferation is controlled during development, and how genetic mutations lead to growth abnormalities and cancer. The model system used in this work is the fruit fly Drosophila, which offers outstanding advantages for experimental developmental biology as well as the essential tools for a systematic molecular genetic analysis of these problems. We are investigating the functions of gene products required to promote cell proliferation in the imaginal discs during larval growth, as well as the gene products required for shutting down cell proliferation at the end of the growth period.

Recent Publications

  • You, X.J., Bryant, P.J., Jurnak, F. and Holcombe, R.F. (2007). Expression of Wnt pathway components frizzled and disheveled in colon cancer arising in patients with inflammatory bowel disease. Oncology Reports 18, 691-4.
  • Doleželová, E., Nothacker H.-P., Civelli O., Bryant P.J. and Žurovec M. (2007). A Drosophila adenosine receptor activates cAMP and calcium signaling. Insect Biochem. Molec. Biol. 37, 318-329.
  • Terskikh, A., Bryant, P.J. and Schwartz, P.H. (2006). Mammalian stem cells. Pediatric Res. 59, 13R-20R.
  • Marble, D. D., Snyder, E. D., Hegle, A. P., Dimitratos, S., Bryant, Peter J. and Wilson, G.F. (2005). Camguk/CASK enhances Ether-a-go-go potassium current by a phosphorylation-dependent mechanism. J. Neurosci. Res. 25, 4898-907.
  • Doleželová, E., Žurovec, M., Dolezal, T., Simek, P. and Bryant, P.J. (2005). The Emerging Role of Adenosine Deaminases in Insects. Insect Biochem. Molec. Biol. 35, 381-9.