UCI
School of Biological Sciences
Developmental and Cell Biology

Pierre Baldi

Pierre Baldi, PhD

Pierre Baldi, Ph.D.
Professor (joint appt.)

4038 Bren Hall
University of California Irvine
Irvine, CA 92697

Tel: (949) 824-5809
Fax: (949) 824-4056
Email: pfbaldi@ics.uci.edu
Website: Lab Homepage

Bioinformatics; Computational Biology - Dr. Baldi’s group works at the intersection of biological and computer sciences, using probabilistic/machine learning techniques to address biological problems and mine large data sets produced by massive data acquisition technologies, such as genome sequencing, high-throughput drug screening, and DNA microarrays. Current projects include the prediction of protein secondary and tertiary structure, the study of DNA structure in relation to several biological processes (protein binding, gene regulation, triplet repeat expansion diseases), and the analysis of gene expression data. Dr. Baldi’s group is building a suite of genomics and proteomics programs for the prediction of protein structure and function and the analysis of microarray data.

Recent Publications

  • A. D. Long, H. J. Mangalam, B. Y. P. Chan, L. Tolleri, G. W. Hatfield, and P. Baldi. Improved Statistical Inference from DNA Microarray Data Using Analysis of Variance and a Bayesian Statistical Framework. Journal of Biological Chemistry, 276,23,19937-19944, (2001).
  • Book: P. Baldi. The Shattered Self-The End of Evolution, MIT Press, in press, (2001).
  • Book: P. Baldi and S. Brunak. Bioinformatics: the Machine Learning Approach, MIT Press, (1998). Second Edition (2001).
  • Book: Pierre Baldi and G. Wesley Hatfield. DNA Microarrays and Gene Regulation, MIT Press,(expected Fall, 2001)
  • G. Pollasti, P. Baldi, P. Fariselli, R. Casadio. Improved Prediction of the Number of Residue Contacts in Proteins by Recurrent Neural Networks. Bioinformatics, 17, Supplement 1, S234-S242, (2001).