UCI
School of Biological Sciences
Developmental and Cell Biology

Steven Gross

Steven Gross, PhD

Steven Gross, Ph.D.
Associate Professor

2222 Natural Sciences I
University of California Irvine
Irvine, CA 92697

Tel: (949) 824-3159
Fax: (949) 824-4709
Email: sgross@uci.edu
Website: Lab Homepage

Laser tweezers; Regulation of molecular motors - My research is quite cross-disciplinary. The majority of biological studies have focused on biochemical or genetic understanding of biological processes, however understanding the relevant physical processes is also important. Proteins physically do things, and to understand the biology, we must start to think about proteins as machines, as well as considering their biochemical properties and genetic regulation. faculty-gross-1.pngWe will soon know the Human Genome, we already know the Drosophila and the C. Elegans Genomes, and yet are very far from understanding how proteins work, and how the exquisitely ordered structures we observe in cells, embryos, and developed organisms come about. Cytoskeletal processes such as transport are important in the creation of this order, and my lab is attempting to develop and apply physical tools to quantify transport as it occurs in living cells.

Recent Publications

  • S. P. Gross*, M. C. Tuma*, S. W. Deacon, A. S. Serpinskaya A. R. Reilein and V. I. Gelfand, “Interactions and Regulation of Molecular Motors in Xenopus Melanophores”, to appear Mar. 4 issue J. Cell Bio., 2002
  • S.P Gross*, M. Welte*, S.M. Block, and E.F. Wieschaus, “Coordination of opposite-polarity microtubule motors”, to appear Feb 18 issue J. Cell Biol., 2002
  • L.W. Enquist, M.J. Tomishima, S. Gross, G.S. Smith, “Directional spread of an alpha-herpsesvirus in the nervous system”, Veter. Microb. 2266, 1-12 (2002).
  • G.A. Smith*, S.P Gross*, and L.W. Enquist, “Herpesviruses use bidirectional fast-axonal transport to spread in sensory neurons”, PNAS 98 3466-70 (2001)
  • S.P Gross, M. Welte, S.M. Block, and E.F. Wieschaus, “Dynein-mediated cargo transport In vivo. A switch controls travel distance.”, J. Cell Biol. 148 945-56 (2000).