February 24, 2024
ucidevcell

Biology, Administration, and Therapy of Small Cell Lung Most cancer

Paradigm Shifts in Mast Cell and Basophil Biology and Operate: An Rising View of Immune Regulation in Well being and Illness

The physiological position of the mast cell and basophil has for a few years remained enigmatic. On this chapter, we briefly summarize a number of the more moderen research that shed new mild on the position of mast cells and basophils in well being and illness

. What we achieve from these research is a brand new appreciation for mast cells and basophils as sentinels in host protection and an extra understanding that dysregulation of mast cell and basophil perform generally is a element of assorted ailments aside from allergy symptoms. 

Maybe a very powerful perception reaped from this work is the rising consciousness that mast cells and basophils can perform as immunoregulatory cells that modulate the immune response in well being and illness. Collectively, the current data supplies new challenges and alternatives towards the event of novel therapeutic methods to enhance host safety and modify illness by manipulation of mast cell and basophil perform.  

Pure killer cells in most cancers biology and remedy

The tumor microenvironment is extremely advanced, and immune escape is at present thought-about an essential hallmark of most cancers, largely contributing to tumor development and metastasis. Named for his or her functionality of killing goal cells autonomously, pure killer (NK) cells function the primary effector cells towards most cancers in innate immunity and are extremely heterogeneous within the microenvironment. 

Most present therapy choices harnessing the tumor microenvironment give attention to T cell-immunity, both by selling activating indicators or suppressing inhibitory ones. The restricted success achieved by T cell immunotherapy highlights the significance of creating new-generation immunotherapeutics, for instance using beforehand ignored NK cells. 

Though tumors additionally evolve to withstand NK cell-induced cytotoxicity, cytokine complement, blockade of suppressive molecules and genetic engineering of NK cells could overcome such resistance with nice promise in each strong and hematological malignancies. On this overview, we summarized the elementary traits and up to date advances of NK cells inside tumor immunometabolic microenvironment, and mentioned potential utility and limitations of rising NK cell-based therapeutic methods within the period of presicion medication.  

Replace on the Biology, Administration, and Therapy of Small Cell Lung Most cancers (SCLC)

Small-cell lung most cancers (SCLC) accounts for 13-15% of all new lung most cancers circumstances within the US. The tumor tends to disseminate early leading to 80-85% of sufferers being identified with in depth illness (ES-SCLC). Chemotherapy has offered SCLC sufferers appreciable survival advantages over the previous three many years. Nonetheless, most sufferers relapse and barely survive past 2 years. 

  • Regardless of constant total response charges of ≥50%, till lately, median survival occasions and 2-year survivals solely ranged between 7-10 months and 10-20%, respectively.
  • A number of chemotherapy brokers possess exercise towards SCLC, each, as single brokers and in mixtures however etoposide-platinum emerged as the popular first line routine.
  • Upon relapse, many sufferers stay candidates for extra remedy. Nonetheless, the sensitivity of relapsed SCLC to additional therapies is markedly decreased and dependent upon the extent and length of response to the preliminary therapy (platinum-sensitive vs. resistant relapse).
  • A number of elements counsel a therapeutic position for immunotherapy in SCLC: SCLC has been related to immune-mediated paraneoplastic processes (cerebellar degeneration, limbic encephalitis, and Lambert-Eaton syndrome) and sufferers presenting with these paraneoplastic syndromes have proven extra favorable outcomes, suggesting an underlying immune response mechanism.
  • Complete genomic profiling of SCLC signifies that almost all lack purposeful p53 (90%) and Rb1 (65%).
  • These common genetic aberrations facilitate poor genomic stability, thus perpetuating the technology of tumor related antigens, amenable to concentrating on with immunotherapy.
  • SCLC has one of many highest mutational masses, probably a mirrored image of the myriad of insults inflicted by smoking-related carcinogens.
  • The connection between tumor mutational load and response to immune checkpoint inhibitors has been established in a number of strong tumors, together with preliminary ends in relapsed SCLC.
  • On this manuscript, we overview the early (some failed and discontinued, some partly profitable, and nonetheless ongoing) makes an attempt to include immunotherapy (significantly vaccine primarily based approaches) to the therapy of SCLC, and the most recent makes an attempt (principally incorporating using checkpoint inhibitors), together with these with favorable however preliminary outcomes (CheckMate 032, Keynote 028 and 158), and people with extra definitive optimistic (iMpower 133 and CASPIAN) and unfavourable (CheckMate 331 and 451) outcomes.
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ucidevcell

Linagliptin

300125 100.0mg
EUR 60

Linagliptin

GP5216-1 1
EUR 173.3

Linagliptin

GP5216-250 250
EUR 77.7

Linagliptin

GP5216-50 50
EUR 36.2

Linagliptin

T0191-10mg 10mg Ask for price
Description: Linagliptin

Linagliptin

T0191-1g 1g Ask for price
Description: Linagliptin

Linagliptin

T0191-1mg 1mg Ask for price
Description: Linagliptin

Linagliptin

T0191-50mg 50mg Ask for price
Description: Linagliptin

Linagliptin

T0191-5mg 5mg Ask for price
Description: Linagliptin

Linagliptin (BI-1356)

A4034-10 10 mg
EUR 157.2
Description: BI1356 is a potent and competitive DPP-4 inhibitor, which exhibited DPP-4 inhibiting activity in several independent tests.

Linagliptin (BI-1356)

A4034-100 100 mg
EUR 282
Description: BI1356 is a potent and competitive DPP-4 inhibitor, which exhibited DPP-4 inhibiting activity in several independent tests.

Linagliptin (BI-1356)

A4034-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: BI1356 is a potent and competitive DPP-4 inhibitor, which exhibited DPP-4 inhibiting activity in several independent tests.

Linagliptin (BI-1356)

A4034-50 50 mg
EUR 212.4
Description: BI1356 is a potent and competitive DPP-4 inhibitor, which exhibited DPP-4 inhibiting activity in several independent tests.

Linagliptin mixture with metformin

T32758-10mg 10mg Ask for price
Description: Linagliptin mixture with metformin

Linagliptin mixture with metformin

T32758-1g 1g Ask for price
Description: Linagliptin mixture with metformin

Linagliptin mixture with metformin

T32758-1mg 1mg Ask for price
Description: Linagliptin mixture with metformin

Linagliptin mixture with metformin

T32758-50mg 50mg Ask for price
Description: Linagliptin mixture with metformin

Linagliptin mixture with metformin

T32758-5mg 5mg Ask for price
Description: Linagliptin mixture with metformin

Lin7a/ Rat Lin7a ELISA Kit

ELI-16232r 96 Tests
EUR 1063.2

Lenti ORF particles, Lin28a (GFP-tagged) - Mouse lin-28 homolog A (Lin28a), 200ul, >10^7 TU/mL

MR202250L4V 200 µl Ask for price

Lenti ORF particles, LIN28A (Myc-DDK tagged) - Human lin-28 homolog A (LIN28A), 200ul, >10^7 TU/mL

RC203397L1V 200 µl Ask for price

Lenti ORF particles, LIN28A (mGFP-tagged) - Human lin-28 homolog A (LIN28A), 200ul, >10^7 TU/mL

RC203397L2V 200 µl Ask for price

Lenti ORF particles, LIN28A (Myc-DDK tagged) - Human lin-28 homolog A (LIN28A), 200ul, >10^7 TU/mL

RC203397L3V 200 µl Ask for price

Lenti ORF particles, LIN28A (mGFP-tagged) - Human lin-28 homolog A (LIN28A), 200ul, >10^7 TU/mL

RC203397L4V 200 µl Ask for price

Lenti ORF particles, Lin28a (Myc-DDK-tagged) - Mouse lin-28 homolog A (Lin28a), 200ul, >10^7 TU/mL

MR202250L3V 200 µl Ask for price

Lenti ORF particles, Lin7a (GFP-tagged ORF) - Rat lin-7 homolog a (C. elegans) (Lin7a), 200ul, >10^7 TU/mL

RR206990L4V 200 µl Ask for price

Lenti ORF particles, LIN7A (Myc-DDK tagged) - Human lin-7 homolog A (C. elegans) (LIN7A), 200ul, >10^7 TU/mL

RC221902L3V 200 µl Ask for price

Lenti ORF particles, LIN7A (mGFP-tagged) - Human lin-7 homolog A (C. elegans) (LIN7A), 200ul, >10^7 TU/mL

RC221902L4V 200 µl Ask for price

Lenti ORF particles, Lin7a (Myc-DDK-tagged ORF) - Rat lin-7 homolog a (C. elegans) (Lin7a), 200ul, >10^7 TU/mL

RR206990L3V 200 µl Ask for price

LIN28A (untagged)-Human lin-28 homolog A (LIN28A)

SC122965 10 µg Ask for price

LIN28A (GFP-tagged) - Human lin-28 homolog A (LIN28A)

RG203397 10 µg Ask for price

Lin28a (untagged) - Mouse lin-28 homolog A (Lin28a), (10ug)

MC204860 10 µg Ask for price

Lin7a (untagged ORF) - Rat lin-7 homolog a (C. elegans) (Lin7a), (10 ug)

RN206990 10 µg Ask for price

LIN7A (untagged)-Human lin-7 homolog A (C. elegans) (LIN7A)

SC108522 10 µg Ask for price

Lin28a (Myc-DDK-tagged) - Mouse lin-28 homolog A (Lin28a)

MR202250 10 µg Ask for price

LIN28A (Myc-DDK-tagged)-Human lin-28 homolog A (LIN28A)

RC203397 10 µg Ask for price

LIN7A (GFP-tagged) - Human lin-7 homolog A (C. elegans) (LIN7A)

RG221902 10 µg Ask for price

Lin7a (Myc-DDK-tagged ORF) - Rat lin-7 homolog a (C. elegans) (Lin7a), (10 ug)

RR206990 10 µg Ask for price

LIN7A (Myc-DDK-tagged)-Human lin-7 homolog A (C. elegans) (LIN7A)

RC221902 10 µg Ask for price

Lenti ORF clone of Lin28a (mGFP-tagged) - Mouse lin-28 homolog A (Lin28a)

MR202250L4 10 µg Ask for price

LIN28A

E8M1301-1 100ul
EUR 275
Description: Available in various conjugation types.

LIN7A

pro-1252 2µg
EUR 60
Description: Recombinant Human LIN7A

Lenti ORF clone of Lin28a (Myc-DDK-tagged) - Mouse lin-28 homolog A (Lin28a)

MR202250L3 10 µg Ask for price

Lenti ORF clone of Lin7a (mGFP-tagged ORF) - Rat lin-7 homolog a (C. elegans) (Lin7a), (10 ug)

RR206990L4 10 µg Ask for price

Lenti ORF clone of Lin7a (Myc-DDK-tagged ORF) - Rat lin-7 homolog a (C. elegans) (Lin7a), (10 ug)

RR206990L3 10 µg Ask for price

LIN28A siRNA

20-abx922588
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

LIN28A siRNA

20-abx922589
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

LIN7A siRNA

20-abx902990
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

LIN7A siRNA

20-abx922598
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

LIN7A siRNA

20-abx922599
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

Lin7a (untagged) - Mouse lin-7 homolog A (C. elegans) (Lin7a), transcript variant 3

MC225687 10 µg Ask for price

Lin7a (untagged) - Mouse lin-7 homolog A (C. elegans) (Lin7a), transcript variant 1, (10ug)

MC212164 10 µg Ask for price

Lin7a (untagged) - Mouse lin-7 homolog A (C. elegans) (Lin7a), transcript variant 2, (10ug)

MC212165 10 µg Ask for price

Lin7a (GFP-tagged) - Mouse lin-7 homolog A (C. elegans) (Lin7a) transcript variant 2, (10ug)

MG219164 10 µg Ask for price

Lin7a (GFP-tagged) - Mouse lin-7 homolog A (C. elegans) (Lin7a) transcript variant 1, (10ug)

MG218556 10 µg Ask for price

Linarin

571440 5.0mg
EUR 235

Linarin

GC6460-10 10
EUR 95

Linarin

GC6460-5 5
EUR 60.1

Linarin

TB0165-0500 20mg
EUR 248.4

Linarin

T6S0653-10mg 10mg Ask for price
Description: Linarin

Linarin

T6S0653-1g 1g Ask for price
Description: Linarin

Linarin

T6S0653-1mg 1mg Ask for price
Description: Linarin

Linarin

T6S0653-50mg 50mg Ask for price
Description: Linarin

Linarin

T6S0653-5mg 5mg Ask for price
Description: Linarin

LIN28A Rabbit mAb

A9627 50μL
EUR 323.7
Description: A synthetic peptide corresponding to a sequence within amino acids 148-247 of human Mast Cell Chymase (CMA1) (CMA1) (P23946).

LIN28A Rabbit mAb

A21261 100μL
EUR 1557.4
Description: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IGHD (P01880).

Lin7a (Myc-DDK-tagged) - Mouse lin-7 homolog A (C. elegans) (Lin7a), transcript variant 1

MR218556 10 µg Ask for price

Lin7a (Myc-DDK-tagged) - Mouse lin-7 homolog A (C. elegans) (Lin7a), transcript variant 2

MR219164 10 µg Ask for price

Lin7a (myc-DDK-tagged) - Mouse lin-7 homolog A (C. elegans) (Lin7a), transcript variant 3

MR227898 10 µg Ask for price

LIN7A Protein

20-abx262552
  • EUR 393.60
  • EUR 7676.40
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

LIN7A Rabbit pAb

A15346-100ul 100 ul
EUR 369.6

LIN7A Rabbit pAb

A15346-200ul 200 ul
EUR 550.8

LIN7A Rabbit pAb

A15346-20ul 20 ul
EUR 219.6

LIN7A Rabbit pAb

A15346-50ul 50 ul
EUR 267.6

Linalool

N2418-20 20 mg
EUR 338.4
Description: Extracted from Cinnamomum camphora (L.) Presl.;Store the product in sealed, cool and dry condition

Linalool

HY-N0368 10mM/1mL
EUR 135.6

Linalool

GP6851-100ML 100 ml
EUR 60

Linalool

GP6851-250ML 250 ml
EUR 84

Linalool

GP6851-500ML 500 ml
EUR 111.6

Linalool

20505-22 25ML
EUR 10.85

Linalool

591716 5.0g
EUR 240

Linalool

GP6851-100 100
EUR 19.8

Linalool

GP6851-250 250
EUR 39.4

Linalool

GP6851-500 500
EUR 62.5

Linalool

TB0563 10X20mg
EUR 328.8

Linariin

TBZ1563 unit Ask for price

Linalool 92%

L03260 100ML
EUR 164.6

Linatine

T25731-10mg 10mg Ask for price
Description: Linatine

Linatine

T25731-1g 1g Ask for price
Description: Linatine

Linatine

T25731-1mg 1mg Ask for price
Description: Linatine

Linatine

T25731-50mg 50mg Ask for price
Description: Linatine

Linatine

T25731-5mg 5mg Ask for price
Description: Linatine

Linalool

T2S2264-10mg 10mg Ask for price
Description: Linalool

Linalool

T2S2264-1g 1g Ask for price
Description: Linalool

Linalool

T2S2264-1mg 1mg Ask for price
Description: Linalool

Linalool

T2S2264-50mg 50mg Ask for price
Description: Linalool

Linalool

T2S2264-5mg 5mg Ask for price
Description: Linalool

LIN28A Antibody

37118-100ul 100ul
EUR 302.4

LIN28A Antibody

1-CSB-PA13619A0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against LIN28A. Recognizes LIN28A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

LIN28A Antibody

1-CSB-PA012958GA01HU
  • EUR 716.40
  • EUR 399.60
  • 150ul
  • 50ul
Description: A polyclonal antibody against LIN28A. Recognizes LIN28A from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF

LIN28A Antibody

1-CSB-PA549629
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against LIN28A. Recognizes LIN28A from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:25-1:100

LIN28A Antibody

CSB-PA586531- each
EUR 402
Description: A polyclonal antibody against LIN28A. Recognizes LIN28A from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

LIN28A Antibody

CSB-PA586531-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against LIN28A. Recognizes LIN28A from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

LIN28A Antibody

F52805-0.08ML 0.08 ml
EUR 140.25
Description: Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 [removed]By similarity). Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let- 7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Degradation of pre- let-7 in embryonic stem (ES) cells contributes to the maintenance of ES cells. In contrast, LIN28A down-regulation in neural stem cells by miR-125, allows the processing of pre-let-7. Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7. Also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'-GGAG-3' motif in the terminal loop, leading to their terminal uridylation and subsequent degradation.

LIN28A Antibody

F52805-0.4ML 0.4 ml
EUR 322.15
Description: Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 [removed]By similarity). Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let- 7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Degradation of pre- let-7 in embryonic stem (ES) cells contributes to the maintenance of ES cells. In contrast, LIN28A down-regulation in neural stem cells by miR-125, allows the processing of pre-let-7. Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7. Also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'-GGAG-3' motif in the terminal loop, leading to their terminal uridylation and subsequent degradation.

Lin28a Antibody

F53240-0.08ML 0.08 ml
EUR 140.25
Description: Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre- let-7. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Degradation of pre-let-7 in embryonic stem (ES) cells contributes to the maintenance of ES cells. In contrast, Lin28a down-regulation in neural stem cells by miR-125, allows the processing of pre-let-7. Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7. Also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'- GGAG-3' motif in the terminal loop, leading to their terminal uridylation and subsequent degradation.

Lin28a Antibody

F53240-0.4ML 0.4 ml
EUR 322.15
Description: Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre- let-7. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Degradation of pre-let-7 in embryonic stem (ES) cells contributes to the maintenance of ES cells. In contrast, Lin28a down-regulation in neural stem cells by miR-125, allows the processing of pre-let-7. Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7. Also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'- GGAG-3' motif in the terminal loop, leading to their terminal uridylation and subsequent degradation.

LIN28A Antibody

F40207-0.08ML 0.08 ml
EUR 140.25
Description: LIN28A is a translational enhancer that drives specific mRNAs to polysomes and increases the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in mRNA stabilization. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression (By similarity). Suppressor of microRNA (miRNA) biogenesis, including that of let-7, miR107, miR-143 and miR-200c. Specifically binds miRNA precursors (pre-miRNAs), recognizing an 5'-GGAG-3' motif found in pre-miRNA terminal loop, and recruits ZCCHC11/TUT4 uridylyltransferase. This results in the terminal uridylation of target pre-miRNAs. Uridylated pre-miRNAs fail to be processed by Dicer and undergo degradation.[UniProt]

LIN28A Antibody

F40207-0.4ML 0.4 ml
EUR 322.15
Description: LIN28A is a translational enhancer that drives specific mRNAs to polysomes and increases the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in mRNA stabilization. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression (By similarity). Suppressor of microRNA (miRNA) biogenesis, including that of let-7, miR107, miR-143 and miR-200c. Specifically binds miRNA precursors (pre-miRNAs), recognizing an 5'-GGAG-3' motif found in pre-miRNA terminal loop, and recruits ZCCHC11/TUT4 uridylyltransferase. This results in the terminal uridylation of target pre-miRNAs. Uridylated pre-miRNAs fail to be processed by Dicer and undergo degradation.[UniProt]

LIN28A Antibody

F41287-0.08ML 0.08 ml
EUR 140.25
Description: Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression (By similarity). Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Degradation of pre-let-7 in embryonic stem (ES) cells contributes to the maintenance of ES cells. In contrast, LIN28A down-regulation in neural stem cells by miR-125, allows the processing of pre-let-7. Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7. Also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'-GGAG-3' motif in the terminal loop, leading to their terminal uridylation and subsequent degradation.

LIN28A Antibody

F41287-0.4ML 0.4 ml
EUR 322.15
Description: Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression (By similarity). Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Degradation of pre-let-7 in embryonic stem (ES) cells contributes to the maintenance of ES cells. In contrast, LIN28A down-regulation in neural stem cells by miR-125, allows the processing of pre-let-7. Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7. Also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'-GGAG-3' motif in the terminal loop, leading to their terminal uridylation and subsequent degradation.

LIN28A Antibody

E037118 100μg/100μl
EUR 255
Description: Available in various conjugation types.

LIN28A Antibody

RQ5665 100 ug
EUR 356.15
Description: Protein lin-28 homolog A is a protein that in humans is encoded by the LIN28A gene. It is mapped to 1p36.11. This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.

LIN28A Antibody

AF7938-100ul 100ul
EUR 350

LIN28A Antibody

AF7938-200ul 200ul
EUR 450

LIN28A Antibody

AF7938-50ul 50ul
EUR 250

LIN28A Antibody

AF7938 100ul
EUR 350
Description: Human,Mouse

LIN7A Antibody

1-CSB-PA012963LA01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against LIN7A. Recognizes LIN7A from Human, Mouse, Zebrafish. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:1000-1:5000

LIN7A Antibody

E309998 200ul
EUR 275
Description: Available in various conjugation types.

Linamarin

2749-25 each
EUR 418.8

Linamarin

2749-50 each
EUR 705.6

Linamarin

328066 5.0mg
EUR 150

Linamarin

GC5398-100 100
EUR 633.9

Linamarin

GC5398-25 25
EUR 281.3

Linamarin

GC5398-250 250
EUR 1286.4

Linamarin

GC5398-50 50
EUR 382.3

Methods biology method to exploring the impact of cyclic stretching on cardiac cell physiology

Though mechanical forces are concerned in pressure-overloaded cardiomyopathy, their results on gene transcription profiles will not be absolutely understood.

Right here, we used next-generation sequencing (NGS) to analyze adjustments in genomic profiles after cyclic mechanical stretching of human cardiomyocytes. 

We discovered that 85, 87, 32, 29, and 28 genes had been differentially expressed after 1, 4, 12, 24, and 48 hours of stretching. Moreover, 10 of the 29 genes that had been up-regulated and 11 of the 28 that had been down-regulated after 24 h confirmed the identical adjustments after 48 h. 

We then examined expression of the genes that encode serpin household E member 1 (SERPINE1), DNA-binding protein inhibitor 1 (ID1), DNA-binding protein inhibitor 3 (ID3), and CCL2, a cytokine that acts as chemotactic think about monocytes, in an RT-PCR experiment.

The identical adjustments had been noticed for all 4 genes in any case cyclic stretching durations, confirming the NGS outcomes. Taken collectively, these findings counsel that cyclical stretching can alter cardiac cell physiology by activating cardiac cell metabolism and impacting ldl cholesterol biosynthesis signaling.

Human Glycophorin A (GYPA) Protein

20-abx066879
  • EUR 794.40
  • EUR 326.40
  • EUR 2448.00
  • EUR 944.40
  • EUR 577.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Glycophorin A (GYPA) CLIA Kit

20-abx493010
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Glycophorin A / CD235a, Fc Tag

E24PHA350 50 μg
EUR 225

Human Glycophorin A (GYPA) ELISA Kit

20-abx151689
  • EUR 8534.40
  • EUR 4550.40
  • EUR 1054.80
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Glycophorin A (GYPA) ELISA Kit

abx573167-96tests 96 tests
EUR 886.8

Human Glycophorin A (GYPA) ELISA Kit

DLR-GYPA-Hu-48T 48T
EUR 597.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Glycophorin A (GYPA) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Glycophorin A (GYPA) ELISA Kit

DLR-GYPA-Hu-96T 96T
EUR 776.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Glycophorin A (GYPA) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Glycophorin- A, GYPA ELISA KIT

ELI-27988h 96 Tests
EUR 988.8

Human Glycophorin A (GYPA) ELISA Kit

SEB704Hu-10x96wellstestplate 10x96-wells test plate
EUR 5402.92
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Glycophorin A (GYPA) in tissue homogenates, cell lysates and other biological fluids.

Human Glycophorin A (GYPA) ELISA Kit

SEB704Hu-1x48wellstestplate 1x48-wells test plate
EUR 550.13
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Glycophorin A (GYPA) in tissue homogenates, cell lysates and other biological fluids.

Human Glycophorin A (GYPA) ELISA Kit

SEB704Hu-1x96wellstestplate 1x96-wells test plate
EUR 734.46
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Glycophorin A (GYPA) in tissue homogenates, cell lysates and other biological fluids.

Human Glycophorin A (GYPA) ELISA Kit

SEB704Hu-5x96wellstestplate 5x96-wells test plate
EUR 2945.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Glycophorin A (GYPA) in tissue homogenates, cell lysates and other biological fluids.

Human Glycophorin A (GYPA) ELISA Kit

4-SEB704Hu
  • EUR 5463.60
  • EUR 2886.00
  • EUR 735.60
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Glycophorin A (GYPA) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Glycophorin A (GYPA) ELISA Kit

EKU04524-48T 48T
EUR 527.66

Human Glycophorin A (GYPA) ELISA Kit

EKU04524-5x96T 5x96T
EUR 3580.55

Human Glycophorin A (GYPA) ELISA Kit

EKU04524-96T 96T
EUR 753.8

Human Glycophorin A (GYPA) ELISA Kit

EKL57745-5x96T 5x96T
EUR 3622.83

Human Glycophorin A (GYPA) ELISA Kit

EKL57745-96T 96T
EUR 762.7

Human Glycophorin A (GYPA) ELISA Kit

EKN45635-48T 48T
EUR 359.87

Human Glycophorin A (GYPA) ELISA Kit

EKN45635-5x96T 5x96T
EUR 2441.98

Human Glycophorin A (GYPA) ELISA Kit

EKN45635-96T 96T
EUR 514.1

Human Glycophorin A ELISA Kit (GYPA)

RK01527 96 Tests
EUR 625.2

Human Glycophorin A (GYPA) ELISA Kit

RDR-GYPA-Hu-48Tests 48 Tests
EUR 626.4

Human Glycophorin A (GYPA) ELISA Kit

RDR-GYPA-Hu-96Tests 96 Tests
EUR 868.8

Human Glycophorin A(GYPA)ELISA Kit

QY-E00590 96T
EUR 433.2

Human Glycophorin A (GYPA) ELISA Kit

RD-GYPA-Hu-48Tests 48 Tests
EUR 600

Human Glycophorin A (GYPA) ELISA Kit

RD-GYPA-Hu-96Tests 96 Tests
EUR 830.4

Human Glycophorin A (GYPA) ELISA Kit

RDR-GYPA-Hu-48T 48T
EUR 453.92
Description: tissue homogenates, cell lysates and other biological fluids.

Human Glycophorin A (GYPA) ELISA Kit

RDR-GYPA-Hu-96T 96T
EUR 648.38
Description: tissue homogenates, cell lysates and other biological fluids.

Human Glycophorin A (GYPA) ELISA Kit

DL-GYPA-Hu 96T
EUR 421
Description: tissue homogenates, cell lysates or other biological fluids.

Human Glycophorin A (GYPA) ELISA Kit

DLR-GYPA-Hu 96T
EUR 443
Description: tissue homogenates, cell lysates or other biological fluids.

Human Glycophorin A (GYPA) ELISA Kit

RD-GYPA-Hu-48T 48T
EUR 432.3
Description: tissue homogenates, cell lysates and other biological fluids.

Human Glycophorin A (GYPA) ELISA Kit

RD-GYPA-Hu-96T 96T
EUR 617.5
Description: tissue homogenates, cell lysates and other biological fluids.

Human Glycophorin A / CD235a, His Tag

E24PHA351 50 μg
EUR 225

Human Glycophorin-A (GYPA) ELISA Kit

RK11216 96T
EUR 280

Human Glycophorin-A(GYPA) ELISA Kit

NSL0573Hu 96 wells
EUR 468

Glycophorin A Peptide

45-067P 0.1 mg
EUR 405.6
Description: (CT) Glycophorin A Peptide

Human GYPA/ Glycophorin-A ELISA Kit

E1078Hu 1 Kit
EUR 726

Recombinant Human Glycophorin-A Protein

RP02835 500μg
EUR 1462.5

Glycophorin A Antibody

48006-100ul 100ul
EUR 399.6

Glycophorin A Antibody

48006-50ul 50ul
EUR 286.8

Glycophorin A Antibody

V7832-100UG 100 ug
EUR 349.3
Description: Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

Glycophorin A Antibody

V7832-20UG 20 ug
EUR 153.3
Description: Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

Glycophorin A Antibody

V7832SAF-100UG 100 ug
EUR 349.3
Description: Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

Glycophorin A Antibody

R36097-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: GYPA

Glycophorin A Antibody

V3313-100UG 100 ug
EUR 349.3
Description: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). [UniProt]

Glycophorin A Antibody

V3313-20UG 20 ug
EUR 153.3
Description: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). [UniProt]

Glycophorin A Antibody

V3313SAF-100UG 100 ug
EUR 349.3
Description: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). [UniProt]

Glycophorin A Antibody

V3328-100UG 100 ug
EUR 349.3
Description: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). [UniProt]

Glycophorin A Antibody

V3328-20UG 20 ug
EUR 153.3
Description: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). [UniProt]

Glycophorin A Antibody

V3328SAF-100UG 100 ug
EUR 349.3
Description: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). [UniProt]

Glycophorin A Antibody

V3604-100UG 100 ug
EUR 349.3
Description: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). [UniProt]

Glycophorin A Antibody

V3604-20UG 20 ug
EUR 153.3
Description: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). [UniProt]

Glycophorin A Antibody

V3604IHC-7ML 7 ml
EUR 349.3
Description: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). [UniProt]

Glycophorin A Antibody

V3604SAF-100UG 100 ug
EUR 349.3
Description: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). [UniProt]

Glycophorin A Antibody

V3725-100UG 100 ug
EUR 349.3
Description: Glycophorin A (MNS blood group), also known as GYPA, is a protein which in humans is encoded by the GYPA gene. GYPA has also been designated CD235a. Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. [Wiki]

Glycophorin A Antibody

V3725-20UG 20 ug
EUR 153.3
Description: Glycophorin A (MNS blood group), also known as GYPA, is a protein which in humans is encoded by the GYPA gene. GYPA has also been designated CD235a. Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. [Wiki]

Glycophorin A Antibody

V3725IHC-7ML 7 ml
EUR 349.3
Description: Glycophorin A (MNS blood group), also known as GYPA, is a protein which in humans is encoded by the GYPA gene. GYPA has also been designated CD235a. Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. [Wiki]

Glycophorin A Antibody

V3725SAF-100UG 100 ug
EUR 349.3
Description: Glycophorin A (MNS blood group), also known as GYPA, is a protein which in humans is encoded by the GYPA gene. GYPA has also been designated CD235a. Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. [Wiki]

Glycophorin A Antibody

V7130-100UG 100 ug
EUR 349.3
Description: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). [UniProt]

Glycophorin A Antibody

V7130-20UG 20 ug
EUR 153.3
Description: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). [UniProt]

Glycophorin A Antibody

V7130IHC-7ML 7 ml
EUR 349.3
Description: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). [UniProt]

Glycophorin A Antibody

V7130SAF-100UG 100 ug
EUR 349.3
Description: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). [UniProt]

Glycophorin A Antibody

V7275-100UG 100 ug
EUR 349.3
Description: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). [UniProt]

Glycophorin A Antibody

V7275-20UG 20 ug
EUR 153.3
Description: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). [UniProt]

Glycophorin A Antibody

V7275IHC-7ML 7 ml
EUR 349.3
Description: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). [UniProt]

Glycophorin A Antibody

V7275SAF-100UG 100 ug
EUR 349.3
Description: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). [UniProt]

Glycophorin A Antibody

V2562-100UG 100 ug
EUR 349.3
Description: Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

Glycophorin A Antibody

V2562-20UG 20 ug
EUR 153.3
Description: Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

Glycophorin A Antibody

V2562IHC-7ML 7 ml
EUR 349.3
Description: Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

Glycophorin A Antibody

V2562SAF-100UG 100 ug
EUR 349.3
Description: Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

Glycophorin A Antibody

V2563-100UG 100 ug
EUR 349.3
Description: Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

Glycophorin A Antibody

V2563-20UG 20 ug
EUR 153.3
Description: Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

Glycophorin A Antibody

V2563IHC-7ML 7 ml
EUR 349.3
Description: Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

Glycophorin A Antibody

V2563SAF-100UG 100 ug
EUR 349.3
Description: Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

Glycophorin A Antibody

RQ5004 100ul
EUR 356.15
Description: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. [UniProt]

Glycophorin A Antibody

E80806-7 100μl
EUR 225
Description: Available in various conjugation types.

Glycophorin A Antibody

DF10170-100ul 100ul
EUR 280

Glycophorin A Antibody

DF10170-200ul 200ul
EUR 350

Glycophorin A Antibody

DF10170 100ul
EUR 280
Description: Human,Rat

Human Glycophorin A, GYPA GENLISA ELISA

KBH4607 1 x 96 wells
EUR 286

ELISA kit for Human GYPA (Glycophorin A)

ELK4771 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Glycophorin A from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Recombinant Human Glycophorin-A (GYPA) ,partial

RPC24701-100ug 100ug
EUR 465.3

Recombinant Human Glycophorin-A (GYPA) ,partial

RPC24701-20ug 20ug
EUR 288.8

Recombinant Human Glycophorin-A (GYPA) ,partial

RPC21424-100ug 100ug
EUR 460.9

Recombinant Human Glycophorin-A (GYPA) ,partial

RPC21424-1mg 1mg
EUR 2237.8

Recombinant Human Glycophorin-A (GYPA) ,partial

RPC21424-20ug 20ug
EUR 258.7

Recombinant Human Glycophorin-A (GYPA) ,partial

RPC28177-100ug 100ug
EUR 440

Recombinant Human Glycophorin-A (GYPA) ,partial

RPC28177-1mg 1mg
EUR 2174.4

Recombinant Human Glycophorin-A (GYPA) ,partial

RPC28177-20ug 20ug
EUR 258.7

GYPA Glycophorin A Human Recombinant Protein

PROTP02724 Regular: 10ug
EUR 380.4
Description: GYPA Human Recombinant produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 81 amino acids (20-91a.a.) and having a molecular mass of 9.1kDa. (Molecular size on SDS-PAGE under reducing conditions 18-28kDa).;GYPA is expressed with a 9 amino acids His tag at C-Terminus and purified by proprietary chromatographic techniques.

Glycophorin A (GYPA) Polyclonal Antibody (Human)

4-PAB704Hu01
  • EUR 286.80
  • EUR 2869.20
  • EUR 717.60
  • EUR 358.80
  • EUR 253.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Glycophorin A (GYPA)

OASB01172-100UG - Human Glycophorin A Antibody

OASB01172-100UG 0.1mg
EUR 129

Glycophorin A (GYPA) Antibody

abx233509-100ug 100 ug
EUR 661.2

Glycophorin A (GYPA) Antibody

20-abx270041
  • EUR 560.40
  • EUR 644.40
  • EUR 326.40
  • EUR 978.00
  • EUR 427.20
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Glycophorin A (GYPA) Antibody

20-abx109828
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Glycophorin A (GYPA) Antibody

20-abx172637
  • EUR 978.00
  • EUR 510.00
  • 1 mg
  • 200 ug

Glycophorin A (GYPA) Antibody

20-abx215783
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

Glycophorin A (GYPA) Antibody

20-abx116844
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Glycophorin A (GYPA) Antibody

abx019097-100ug 100 ug
EUR 410.4

Glycophorin A (GYPA) Antibody

20-abx101088
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Glycophorin A (GYPA) Antibody

20-abx101089
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Glycophorin A (GYPA) Antibody

20-abx123499
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Glycophorin A (GYPA) Antibody

20-abx323344
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Glycophorin A (GYPA) Antibody

abx432755-200ul 200 ul
EUR 460.8

anti- Glycophorin A antibody

FNab03509 100µg
EUR 702
Description: Antibody raised against Glycophorin A

OPCA00110-1MG - Recombinant human Glycophorin-A

OPCA00110-1MG 1mg
EUR 1379

OPCA00110-20UG - Recombinant human Glycophorin-A

OPCA00110-20UG 20ug
EUR 218

OPCA01243-20UG - Recombinant human Glycophorin-A

OPCA01243-20UG 20ug
EUR 258

OPCA00110-100UG - Recombinant human Glycophorin-A

OPCA00110-100UG 100ug
EUR 323

OPCA01243-100UG - Recombinant human Glycophorin-A

OPCA01243-100UG 100ug
EUR 380

Glycophorin-A (CD235a) Antibody

20-abx134182
  • EUR 427.20
  • EUR 678.00
  • EUR 360.00
  • 100 ul
  • 200 ul
  • 50 ul

Glycophorin-A (CD235a) Antibody

abx200508-100ug 100 ug
EUR 393.6

Glycophorin-A (CD235a) Antibody

abx139478-01mg 0.1 mg
EUR 444

Glycophorin-A (CD235a) Antibody

abx139479-01mg 0.1 mg
EUR 427.2

Glycophorin-A (CD235a) Antibody

20-abx141232
  • EUR 427.20
  • EUR 644.40
  • EUR 260.40
  • 100 ul
  • 200 ul
  • 30 ul

Glycophorin-A (CD235a) Antibody

abx411377-1ml 1 ml
EUR 560.4

Glycophorin-A (CD235a) Antibody

abx415004-02mg 0.2 mg
EUR 678

Recombinant Glycophorin A (GYPA)

RPU41703-100ug 100ug
EUR 517

Recombinant Glycophorin A (GYPA)

RPU41703-1mg 1mg
EUR 2293.2

Recombinant Glycophorin A (GYPA)

RPU41703-50ug 50ug
EUR 415.8

Recombinant Glycophorin A (GYPA)

RPU41704-100ug 100ug
EUR 554.4

Recombinant Glycophorin A (GYPA)

RPU41704-1mg 1mg
EUR 2457

Recombinant Glycophorin A (GYPA)

RPU41704-50ug 50ug
EUR 445.5

Recombinant Glycophorin A (GYPA)

4-RPB704Hu01
  • EUR 571.58
  • EUR 276.00
  • EUR 1813.44
  • EUR 684.48
  • EUR 1248.96
  • EUR 458.40
  • EUR 4353.60
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Glycophorin A expressed in: E.coli

Recombinant Glycophorin A (GYPA)

4-RPB704Mu01
  • EUR 603.84
  • EUR 285.60
  • EUR 1934.40
  • EUR 724.80
  • EUR 1329.60
  • EUR 480.00
  • EUR 4656.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Glycophorin A expressed in: E.coli

Rat Glycophorin A ELISA kit

E02G0290-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Glycophorin A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Glycophorin A ELISA kit

E02G0290-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Glycophorin A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Glycophorin A ELISA kit

E02G0290-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Glycophorin A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Glycophorin A ELISA kit

E07G0290-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Glycophorin A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Glycophorin A ELISA kit

E07G0290-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Glycophorin A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Glycophorin A ELISA kit

E07G0290-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Glycophorin A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Glycophorin A ELISA kit

E08G0290-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Glycophorin A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

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