December 1, 2022
ucidevcell

Dewetting: From Physics to the Biology of Intoxicated Cells

Dewetting: From Physics to the Biology of Intoxicated Cells

 Pathogenic micro organism colonize or disseminate into cells and tissues by inducing large-scale remodeling of host membranes. The bodily phenomena underpinning these big membrane extension and deformation are poorly understood. Invasive strategies of pathogens have been simply recently enriched by the define of a spectacular mode of opening of huge transendothelial cell macroaperture (TEM) tunnels correlated to the dissemination of EDIN-producing strains of Staphylococcus aureus by means of a hematogenous route or to the induction of gelatinous edema triggered by the edema toxin from Bacillus anthracis.

Remarkably, these extraordinarily dynamic tunnels shut shortly after they attain a maximal measurement. Opening and closure of TEMs in cells lasts for hours with out inducing endothelial cell demise. Multidisciplinary analysis have started to produce a broader perspective of every the molecular determinants controlling cytoskeleton group at newly curved membranes generated by the opening of TEMs and the bodily processes controlling the dynamics of these tunnels.

Proper right here we speak in regards to the analogy between the opening of TEM tunnels and the bodily concepts of dewetting, stemming from a parallel between membrane stress and ground stress. This analogy provides a broad framework to analysis biophysical constraints in cell membrane dynamics and their diversion by positive invasive microbial brokers

Present advances in myeloid-derived suppressor cell biology

 

In latest occasions, discovering out the place of myeloid-derived suppressor cells (MDSCs) in numerous pathological inflammatory conditions has become a very energetic evaluation area. Although the place of MDSCs in most cancers is relatively successfully established, their place in non-cancerous pathological conditions stays in its infancy resulting in rather a lot confusion. Our targets on this overview are to cope with some present advances in MDSC evaluation in order to lower such confusion and to produce an notion into their function inside the context of various illnesses.

The following issues is perhaps significantly centered upon:

(1) definition and characterization of MDSCs;

(2) whether or not or not all MDSC populations embrace immature cells;

(3) technical factors in MDSC isolation, estimation and characterization;

(4) the origin of MDSCs and their anatomical distribution in effectively being and sickness;

(5) mediators of MDSC development and accumulation;

(6) parts that determine the expansion of 1 MDSC inhabitants over the other;

(7) the Yin and Yang roles of MDSCs. Moreover, the capabilities of MDSCs is perhaps addressed all by the textual content material.

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EHHADH Blocking Peptide

6678BP-50
EUR 183.6

KC Blocking Peptide

5212BP-50
EUR 183.6

CXCR4 Blocking Peptide

5541BP-50
EUR 183.6

DAP12 Blocking Peptide

5570RBP-50
EUR 183.6

MIF Blocking Peptide

5571BP-50
EUR 183.6

Ghrelin Blocking Peptide

5992BP-50
EUR 183.6

Synapsin Blocking Peptide

6008BP-50
EUR 183.6

GDNF Blocking Peptide

5098BP-50
EUR 183.6

ACTH Blocking Peptide

A1051BP-50
EUR 183.6

Secretin Blocking Peptide

A1054BP-50
EUR 183.6

AAK1 Blocking Peptide

3810BP-50
EUR 183.6

Calnexin Blocking Peptide

3811BP-50
EUR 183.6

HSF1 Blocking Peptide

3812BP-50
EUR 183.6

ATGL Blocking Peptide

3814BP-50
EUR 183.6

YAP1 Blocking Peptide

3815BP-50
EUR 183.6

CCR4 Blocking Peptide

3817BP-50
EUR 183.6

GPV1 Blocking Peptide

3818BP-50
EUR 183.6

MGMT Blocking Peptide

3820BP-50
EUR 183.6

Sox1 Blocking Peptide

3822BP-50
EUR 183.6

DPPA4 Blocking Peptide

3826BP-50
EUR 183.6

ASAH2 Blocking Peptide

3828BP-50
EUR 183.6

LASS5 Blocking Peptide

3830BP-50
EUR 183.6

FRS2 Blocking Peptide

3836BP-50
EUR 183.6

ADFP Blocking Peptide

3837BP-50
EUR 183.6

LDLR Blocking Peptide

3839BP-50
EUR 183.6

Trek1 Blocking Peptide

3841BP-50
EUR 183.6

ECM Blocking Peptide

3843BP-50
EUR 183.6

DMP1 Blocking Peptide

3844BP-50
EUR 183.6

DGAT1 Blocking Peptide

3845BP-50
EUR 183.6

Brk Blocking Peptide

3847BP-50
EUR 183.6

DKK1 Blocking Peptide

3851BP-50
EUR 183.6

HDLBP Blocking Peptide

3853BP-50
EUR 183.6

Insig1 Blocking Peptide

3854BP-50
EUR 183.6

Matriptase Blocking Peptide

3855BP-50
EUR 183.6

SOCS1 Blocking Peptide

3861BP-50
EUR 183.6

SCD Blocking Peptide

3875BP-50
EUR 183.6

TFAM Blocking Peptide

3885BP-50
EUR 183.6

Sp3 Blocking Peptide

3887BP-50
EUR 183.6

Boris Blocking Peptide

3888BP-50
EUR 183.6

OX40 Blocking Peptide

3890BP-50
EUR 183.6

FoxH1 Blocking Peptide

3892BP-50
EUR 183.6

DKK3 Blocking Peptide

3893BP-50
EUR 183.6

DKK4 Blocking Peptide

3894BP-50
EUR 183.6

BLAME Blocking Peptide

3895BP-50
EUR 183.6

CLOCK Blocking Peptide

3896BP-50
EUR 183.6

DPP10 Blocking Peptide

3898BP-50
EUR 183.6

Hemopexin Blocking Peptide

3899BP-50
EUR 183.6

LAMP2 Blocking Peptide

3900BP-50
EUR 183.6

EDEM1 Blocking Peptide

3904BP-50
EUR 183.6

PAK1 Blocking Peptide

3908BP-50
EUR 183.6

PAK6 Blocking Peptide

3927BP-50
EUR 183.6

PINK1 Blocking Peptide

3929BP-50
EUR 183.6

TLR11 Blocking Peptide

3931BP-50
EUR 183.6

TLR10 Blocking Peptide

3932BP-50
EUR 183.6

Adipsin Blocking Peptide

3937BP-50
EUR 183.6

ALK7 Blocking Peptide

3938BP-50
EUR 183.6

AdipoR1 Blocking Peptide

3940BP-50
EUR 183.6

TP2 Blocking Peptide

3941BP-50
EUR 183.6

GLUT4 Blocking Peptide

3945BP-50
EUR 183.6

DNMT1 Blocking Peptide

3946BP-50
EUR 183.6

LPL Blocking Peptide

3947BP-50
EUR 183.6

LKB1 Blocking Peptide

3950BP-50
EUR 183.6

AMPK Blocking Peptide

3951BP-50
EUR 183.6

TORC2 Blocking Peptide

3953BP-50
EUR 183.6

TSC1 Blocking Peptide

3955BP-50
EUR 183.6

PDE3B Blocking Peptide

3956BP-50
EUR 183.6

Rictor Blocking Peptide

3957BP-50
EUR 183.6

PI3K Blocking Peptide

3959BP-50
EUR 183.6

SREBP1 Blocking Peptide

3961BP-50
EUR 183.6

TSC2 Blocking Peptide

3962BP-50
EUR 183.6

Sin1 Blocking Peptide

3971BP-50
EUR 183.6

ACADSB Blocking Peptide

3157BP-50
EUR 183.6

Survivin Blocking Peptide

3160BP-50
EUR 183.6

Bid Blocking Peptide

3172BP-50
EUR 183.6

Synaptotagmin Blocking Peptide

3177BP-50
EUR 183.6

CD40L Blocking Peptide

3178BP-50
EUR 183.6

XIAP Blocking Peptide

3183BP-50
EUR 183.6

Perforin Blocking Peptide

3188RBP-50
EUR 183.6

NIK Blocking Peptide

3193RBP-50
EUR 183.6

TrkA Blocking Peptide

3194BP-50
EUR 183.6

SETD3 Blocking peptide

3197BP-50
EUR 183.6

MeCP2 Blocking Peptide

3199BP-50
EUR 183.6

AIF Blocking Peptide

3202BP-50
EUR 183.6

GFAP Blocking Peptide

3206BP-50
EUR 183.6

DR6 Blocking Peptide

3216RBP-50
EUR 183.6

SIRT3 Blocking Peptide

3223BP-50
EUR 183.6

SIRT4 Blocking Peptide

3224BP-50
EUR 183.6

SIRT5 Blocking Peptide

3225BP-50
EUR 183.6

DNMT3a Blocking peptide

3227BP-50
EUR 183.6

NAIP Blocking Peptide

3228BP-50
EUR 183.6

Daxx Blocking Peptide

3229BP-50
EUR 183.6

MBD2a Blocking Peptide

3232BP-50
EUR 183.6

SALL1 Blocking Peptide

3237BP-50
EUR 183.6

SIAH3 Blocking Peptide

3238BP-50
EUR 183.6

ACADVL Blocking Peptide

3240BP-50
EUR 183.6

TRIM71 Blocking Peptide

3241BP-50
EUR 183.6

EZH2 Blocking Peptide

3242BP-50
EUR 183.6

MyD88 Blocking Peptide

3244RBP-50
EUR 183.6

ACAT1 Blocking Peptide

3245BP-50
EUR 183.6

Akt Blocking Peptide

3247BP-50
EUR 183.6

Gai2 Blocking Peptide

3249BP-50
EUR 183.6

TLR4 Blocking Peptide

3253BP-50
EUR 183.6

ACAT2 Blocking Peptide

3254BP-50
EUR 183.6

PARD3 Blocking Peptide

3260BP-50
EUR 183.6

TCTN2 Blocking Peptide

3262BP-50
EUR 183.6

BAK1 Blocking Peptide

3031BP-50
EUR 183.6

Bax Blocking Peptide

3032BP-50
EUR 183.6

p53 Blocking Peptide

3036RBP-50
EUR 183.6

RAIDD Blocking Peptide

3037BP-50
EUR 183.6

NFkB Blocking Peptide

3038BP-50
EUR 183.6

FADD Blocking Peptide

3039BP-50
EUR 183.6

PBR Blocking Peptide

3044BP-50
EUR 183.6

MBD4 Blocking Peptide

3056BP-50
EUR 183.6

PRMT7 blocking peptide

3059BP-50
EUR 183.6

DR4 Blocking Peptide

3061BP-50
EUR 183.6

DR5 Blocking Peptide

3062BP-50
EUR 183.6

CD40 Blocking Peptide

3072BP-50
EUR 183.6

Calreticulin Blocking Peptide

3077BP-50
EUR 183.6

PRMT6 Blocking Peptide

3086BP-50
EUR 183.6

TCTN1 Blocking Peptide

3087BP-50
EUR 183.6

TCTN1 Blocking Peptide

3088BP-50
EUR 183.6

KLF4 Blocking Peptide

3089BP-50
EUR 183.6

Lin28 Blocking Peptide

3091BP-50
EUR 183.6

MRGPRX2 indicators its significance in cutaneous mast cell biology: Does MRGPRX2 be part of mast cells and atopic dermatitis?

 

The invention of MRGPRX2 marks a necessary change in MC biology, explaining non-IgE-mediated scientific phenomena relying on MCs. As receptor for quite a few remedy, MRGPRX2 is important to drug-induced hypersensitivity.

Nonetheless, not solely remedy, however moreover endogenous mediators like neuropeptides and host safety peptides activate MRGPRX2, suggesting its broad affect in cutaneous pathophysiology.

Proper right here, we give a brief overview of MRGPRX2 and its regulation by microenvironmental stimuli, which assist MCs and shall be altered in pores and pores and skin points, and briefly contact on the purposeful packages elicited by MRGPRX2 ligation. Analysis in Mrgprb2-deficient mice (the murine ortholog) help illuminate MRGPRX2’s function in effectively being and sickness.

Present advances on this model assist the long-suspected operational unit between MCs and nerves, with MRGPRX2 being an vital component. Based on the restricted proof for a big contribution of FcεRI/IgE-activated MCs to atopic dermatitis (AD), we develop the hypothesis that MRGPRX2 constitutes the missing hyperlink connecting MCs and AD, a minimum of in chosen endotypes.

Help comes from the multifold changes inside the MC-neuronal system of AD pores and pores and skin (e.g. bigger density of MCs and nearer connections between MCs and nerves, elevated PAR-2/Substance P).

We theorize that these deregulations suffice to impress AD, nonetheless exterior triggers, numerous which activating MRGPRX2 themselves (e.g. Staphylococcus aureus) extra feed into the loop. Itch, most likely probably the most burdensome hallmark of AD, is usually non-histaminergic nonetheless tryptase-dependent, and tryptase is preferentially launched upon MRGPRX2 activation. On account of MRGPRX2 is a very energetic evaluation space, a couple of of the current gaps are susceptible to be closed shortly.

Non-Muscle Myosin II in Axonal Cell Biology: From the Growth Cone to the Axon Preliminary Part

 

By binding to actin filaments, non-muscle myosin II (NMII) generates actomyosin networks that preserve distinctive contractile properties. Their dynamic nature is vital for neuronal biology along with the establishment of polarity, progress cone formation and motility, axon progress all through enchancment (and axon regeneration inside the grownup), radial and longitudinal axonal stress, and synapse formation and efficiency.

On this overview, we speak in regards to the current information on the spatial distribution and efficiency of the actomyosin cytoskeleton in quite a few axonal compartments.

We highlight a couple of of the plain contradictions and open questions inside the space, along with the place of NMII inside the regulation of axon progress and regeneration, the possibility that NMII structural affiliation alongside the axon shaft would possibly administration every radial and longitudinal contractility, and the mechanism and purposeful goal underlying NMII enrichment inside the axon preliminary part.

With the advances in reside cell imaging and super choice microscopy, it is anticipated that inside the near future the spatial distribution of NMII inside the axon, and the mechanisms by which it participates in axonal biology is perhaps extra untangled.

Asterric Acid

A132-5MG 5 mg
EUR 1006.8

Zoledronic Acid

A1352-100 100 mg
EUR 268.8
Description: Zoledronic acid, one of the most potent nitrogen-containing bisphosphonates, induces anti-proliferative and apoptotic effects on multiple myeloma cell lines in vitro by activating protein kinase C. Zoledronic acid also inhibits proliferation of human foet

Zoledronic Acid

A1352-25 25 mg
EUR 129.6
Description: Zoledronic acid, one of the most potent nitrogen-containing bisphosphonates, induces anti-proliferative and apoptotic effects on multiple myeloma cell lines in vitro by activating protein kinase C. Zoledronic acid also inhibits proliferation of human foet

Zoledronic Acid

A1352-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: Zoledronic acid, one of the most potent nitrogen-containing bisphosphonates, induces anti-proliferative and apoptotic effects on multiple myeloma cell lines in vitro by activating protein kinase C. Zoledronic acid also inhibits proliferation of human foet

Pressinoic Acid

5-01806 4 x 5mg Ask for price

Carnosic Acid

2075-25
EUR 523.2

Carnosic Acid

2075-5
EUR 176.4

MB acid

40076 5MG
EUR 384
Description: Minimum order quantity: 1 unit of 5MG

Mycophenolic acid

10-030 500 mg
EUR 539.16
Description: Antibiotic [1]. Shows antiviral, antifungal and antitumor properties [1, 2]. Immunosuppressive drug used to prevent rejection in organ transplantation, rheumatoid arthritis, and psoriasis [3-6, 13]. Potent reversible inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH), leading to depletion of GMP and interruption of the de novo synthesis of purine nucleotides necessary for B and T lymphocyte proliferation [7, 8]. Inhibits the type II IMPDH isoform (IMPDH-2) 5-fold more potently compared to type I isoform [11]. Inhibits RNA and DNA synthesis [13]. Inducible nitric oxide synthase (iNOS/NOS II) inhibitor [8, 10]. Apoptosis and necrosis inducer [9, 12]. Novel type of inhibitor against RNA guanylyltransferases [14]. Inhibits TNF-α-stimulated MAPK/NF-κB and ROS generation [15]. Autophagy suppressor. Broad-spectrum antiviral compound with inhibitory activity against different coronavirus, including SARS-CoV, MERS-CoV and SARS-CoV-2, cause of COVID-19. It binds to the active site of SARS-CoV-2 papain-like protease (PLpro) possibly inhibiting viral replication.

Oleanolic Acid

1731-100
EUR 138

Oleanolic Acid

1731-500
EUR 398.4

Rosmarinic Acid

1843-250
EUR 274.8

Rosmarinic Acid

1843-50
EUR 138

Anacardic Acid

1849-25
EUR 444

Anacardic Acid

1849-5
EUR 176.4

Mycophenolic Acid

1882-250
EUR 352.8

Mycophenolic Acid

1882-50
EUR 138

ICG acid

189 5 mg
EUR 262.8

Arachidonic Acid

1505-100
EUR 202.8

Aurintricarboxylic acid

1506-1000
EUR 164.4

Okadaic acid

1543-025
EUR 188.4

Okadaic acid

1543-100
EUR 379.2

Betulinic acid

1552-100
EUR 450

Betulinic acid

1552-25
EUR 170.4

Lithocholic acid

2187-1G
EUR 138

Lithocholic acid

2187-5G
EUR 326.4

Heptelidic Acid

2215-1000
EUR 588

Heptelidic Acid

2215-250
EUR 261.6

Retinoic acid

2218-250
EUR 405.6

Retinoic acid

2218-50
EUR 151.2

Kainic acid

2279-25
EUR 457.2

Kainic acid

2279-5
EUR 170.4

Caffeic acid

2303-250
EUR 235.2

Caffeic acid

2303-50
EUR 117.6

Gambogic acid

2785-25
EUR 652.8

Gambogic acid

2785-5
EUR 210

Chenodeoxycholic acid

2831-1G
EUR 144

Chenodeoxycholic acid

2831-25G
EUR 574.8

Chenodeoxycholic acid

2831-5G
EUR 222

(+)-Abscisic acid

2543-1
EUR 144

(+)-Abscisic acid

2543-5
EUR 379.2

Itaconic acid

2576-1G
EUR 144

Itaconic acid

2576-5G
EUR 288

Ellagic acid

A2306-25 25 mg
EUR 199.2
Description: Selective, ATP-competitive inhibitor of casein kinase 2 (CK2) (IC50 values are 40, 2900, 3500, 4300 and 9400 nM for CK2, Lyn, PKA, Syk?and FGR respectively). Exhibits antioxidant, antitumor and anticarcinogenic activity and also inhibits glutat

Ellagic acid

A2306-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: Selective, ATP-competitive inhibitor of casein kinase 2 (CK2) (IC50 values are 40, 2900, 3500, 4300 and 9400 nM for CK2, Lyn, PKA, Syk?and FGR respectively). Exhibits antioxidant, antitumor and anticarcinogenic activity and also inhibits glutat

Betulinic acid

A3237-100 100 mg
EUR 129.6
Description: Betulinic acid is a natural pentacyclic triterpenoid that displays anti-HIV and antitumor activity. Betulinic acid selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism.

Betulinic acid

A3237-200 200 mg
EUR 177.6
Description: Betulinic acid is a natural pentacyclic triterpenoid that displays anti-HIV and antitumor activity. Betulinic acid selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism.

Betulinic acid

A3237-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: Betulinic acid is a natural pentacyclic triterpenoid that displays anti-HIV and antitumor activity. Betulinic acid selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism.

Betulinic acid

A3237-500 500 mg
EUR 309.6
Description: Betulinic acid is a natural pentacyclic triterpenoid that displays anti-HIV and antitumor activity. Betulinic acid selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism.

Gambogic Acid

A3424-10 10 mg
EUR 192
Description: Gambogic acid (GA) is an inducer of apoptosis with EC50 value of 0.78-1.64 ?M for caspases and with IC50 values of 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 ?M for Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1, respectively.

Gambogic Acid

A3424-25 25 mg
EUR 261.6
Description: Gambogic acid (GA) is an inducer of apoptosis with EC50 value of 0.78-1.64 ?M for caspases and with IC50 values of 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 ?M for Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1, respectively.

Gambogic Acid

A3424-5 5 mg
EUR 150
Description: Gambogic acid (GA) is an inducer of apoptosis with EC50 value of 0.78-1.64 ?M for caspases and with IC50 values of 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 ?M for Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1, respectively.

Gambogic Acid

A3424-5.1 10 mM (in 1mL DMSO)
EUR 184.8
Description: Gambogic acid (GA) is an inducer of apoptosis with EC50 value of 0.78-1.64 ?M for caspases and with IC50 values of 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 ?M for Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1, respectively.

Anacardic acid

A4488-10 10 mg
EUR 142.8
Description: IC50: Noncompetitively inhibit histone acetyltransferase (HAT) activity in prostate cancer with an IC50 value of about 5.0 M.Anacardic acid (AA) is commonly regarded as a non-specific HAT inhibitor of p300.

Anacardic acid

A4488-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: IC50: Noncompetitively inhibit histone acetyltransferase (HAT) activity in prostate cancer with an IC50 value of about 5.0 M.Anacardic acid (AA) is commonly regarded as a non-specific HAT inhibitor of p300.

Anacardic acid

A4488-50 50 mg
EUR 393.6
Description: IC50: Noncompetitively inhibit histone acetyltransferase (HAT) activity in prostate cancer with an IC50 value of about 5.0 M.Anacardic acid (AA) is commonly regarded as a non-specific HAT inhibitor of p300.

Okadaic acid

A4540-.05 50 µg
EUR 182.4
Description: Okadaic acid is a potent inhibitor of protein phosphatase 1/2A with IC50 values of 19 nM and 0.2 nM for protein phosphatase 1 and protein phosphatase 2A, respectively [1].

Okadaic acid

A4540-.1 100 µg
EUR 292.8
Description: Okadaic acid is a potent inhibitor of protein phosphatase 1/2A with IC50 values of 19 nM and 0.2 nM for protein phosphatase 1 and protein phosphatase 2A, respectively [1].

Abscisic Acid

abx082046-100mg 100 mg
EUR 243.6

Folic acid

abx082263-100g 100 g
EUR 376.8

Folic acid

20-abx082265
  • EUR 376.80
  • EUR 276.00
  • 100 g
  • 25 g

Nicotinic acid

20-abx082297
  • EUR 292.80
  • EUR 243.60
  • 100 g
  • 25 g

Maleic acid

abx082326-100g 100 g
EUR 226.8

Pyruvic acid

20-abx082337
  • EUR 343.20
  • EUR 243.60
  • 100 g
  • 25 g

Boric acid

abx082355-500g 500 g
EUR 243.6

Gibberellic acid

20-abx082365
  • EUR 276.00
  • EUR 226.80
  • 1 g
  • 250 mg

Boric acid

abx082375-500g 500 g
EUR 226.8

Pyruvic acid

20-abx082493
  • EUR 276.00
  • EUR 226.80
  • 100 g
  • 25 g

Lipoteichoic Acid

abx087002-1mg 1 mg
EUR 343.2

Calconcarboxylic Acid

abx090682-25g 25 g
EUR 243.6

Carnosic acid

20-abx076520
  • EUR 292.80
  • EUR 477.60
  • 10 mg
  • 50 mg

Betulinic Acid

20-abx076536
  • EUR 292.80
  • EUR 560.40
  • 10 mg
  • 50 mg

Kainic acid

20-abx076647
  • EUR 444.00
  • EUR 1262.40
  • 10 mg
  • 50 mg

Quisqualic Acid

20-abx076651
  • EUR 510.00
  • EUR 1412.40
  • 10 mg
  • 50 mg

Retinoic acid

20-abx076656
  • EUR 292.80
  • EUR 243.60
  • 250 mg
  • 50 mg

Okadaic acid

20-abx076703
  • EUR 627.60
  • EUR 309.60
  • 100 ug
  • 20 ug

(+)-Abscisic Acid

abx076833-1mg 1 mg
EUR 493.2

Tropodithietic acid

abx076844-1mg 1 mg
EUR 477.6

Piromidic Acid

A8502-10 10 mg
EUR 129.6
Description: Shown to have antibacterial properties.

Piromidic Acid

A8502-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: Shown to have antibacterial properties.

Piromidic Acid

A8502-50 50 mg
EUR 199.2
Description: Shown to have antibacterial properties.

Ascorbic acid

A8158-10 10 mg
EUR 170.4
Description: Ascorbic acid is the recommended reagent for the reduction of Copper(II)-TBTA complex into active Copper(I) form.

Lithocholic Acid

A8463-5.1 10 mM (in 1mL DMSO)
EUR 135.6
Description: Lithocholic acid (LCA) is a toxic secondary bile acid, causing intrahepatic cholestasis, which has tumor-promoting activity.

Lithocholic Acid

A8463-50 50 mg
EUR 157.2
Description: Lithocholic acid (LCA) is a toxic secondary bile acid, causing intrahepatic cholestasis, which has tumor-promoting activity.

Nordihydroguaiaretic acid

A3664-100 100 mg
EUR 126
Description: Description: IC50 Value: N/A Nordihydroguaiaretic acid (NDGA) is a natural phenolic compound isolated from the creosote bush Larrea divaricata, which has anti-tumor activities both in vitro and in vivo.

Nordihydroguaiaretic acid

A3664-500 500 mg
EUR 195.6
Description: Description: IC50 Value: N/A Nordihydroguaiaretic acid (NDGA) is a natural phenolic compound isolated from the creosote bush Larrea divaricata, which has anti-tumor activities both in vitro and in vivo.

Oseltamivir acid

A3689-10 10 mg
EUR 172.8
Description: Oseltamivir is an inhibitor of influenza neuraminidase [1].Oseltamivir is a prodrug that is converted by intestinal and/or hepatic esterases to the neuraminidase inhibitor molecule, oseltamivir carboxylate.

Oseltamivir acid

A3689-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: Oseltamivir is an inhibitor of influenza neuraminidase [1].Oseltamivir is a prodrug that is converted by intestinal and/or hepatic esterases to the neuraminidase inhibitor molecule, oseltamivir carboxylate.

Oseltamivir acid

A3689-50 50 mg
EUR 315.6
Description: Oseltamivir is an inhibitor of influenza neuraminidase [1].Oseltamivir is a prodrug that is converted by intestinal and/or hepatic esterases to the neuraminidase inhibitor molecule, oseltamivir carboxylate.

Anacardic Acid

A160-10MG 10mg
EUR 144

Anacardic Acid

A160-250MG 250mg
EUR 298.8

Glycerophosphoric acid

20-abx180002
  • EUR 260.40
  • EUR 944.40
  • EUR 427.20
  • 1 g
  • 25 g
  • 5 g

Cyclobutylboronic Acid

20-abx180715
  • EUR 410.40
  • EUR 828.00
  • 1 g
  • 5 g

Hendecanoic acid

20-abx180775
  • EUR 376.80
  • EUR 276.00
  • 100 g
  • 25 g

Heptadecanoic acid

20-abx180776
  • EUR 260.40
  • EUR 460.80
  • EUR 326.40
  • 1 g
  • 25 g
  • 5 g

Methanesulfonylacetic Acid

20-abx180797
  • EUR 292.80
  • EUR 1011.60
  • EUR 477.60
  • 1 g
  • 25 g
  • 5 g

Octadecanedioic acid

20-abx180854
  • EUR 861.60
  • EUR 326.40
  • EUR 1528.80
  • EUR 577.20
  • 10 g
  • 1 g
  • 25 g
  • 5 g

pentadecanoic acid

20-abx180857
  • EUR 393.60
  • EUR 260.40
  • 25 g
  • 5 g

Pyromeconic acid

20-abx180870
  • EUR 627.60
  • EUR 1412.40
  • 1 g
  • 5 g

Tridecanoic acid

20-abx180912
  • EUR 260.40
  • EUR 393.60
  • 1 g
  • 5 g

Cyclopentylboronic Acid

20-abx181255
  • EUR 861.60
  • EUR 393.60
  • EUR 2781.60
  • EUR 260.40
  • 100 g
  • 25 g
  • 500 g
  • 5 g

Cyclopropylacetic acid

20-abx181256
  • EUR 2682.00
  • EUR 978.00
  • 100 g
  • 25 g

Hydroxymalonic acid

20-abx181299
  • EUR 944.40
  • EUR 2414.40
  • 1 g
  • 5 g

Tridecanedioic acid

20-abx181373
  • EUR 393.60
  • EUR 276.00
  • EUR 828.00
  • 100 g
  • 25 g
  • 500 g

Coumalic acid

20-abx182402
  • EUR 760.80
  • EUR 292.80
  • 100 g
  • 10 g

Cyclohexylboronic Acid

20-abx182406
  • EUR 243.60
  • EUR 610.80
  • EUR 343.20
  • 1 g
  • 25 g
  • 5 g

Ethylboronic Acid

20-abx182474
  • EUR 744.00
  • EUR 292.80
  • EUR 210.00
  • EUR 376.80
  • EUR 243.60
  • 100 g
  • 10 g
  • 1 g
  • 25 g
  • 5 g

Isopropylboronic Acid

20-abx182498
  • EUR 944.40
  • EUR 309.60
  • EUR 410.40
  • EUR 260.40
  • 100 g
  • 10 g
  • 25 g
  • 5 g

Methylboronic Acid

20-abx182574
  • EUR 393.60
  • EUR 260.40
  • EUR 910.80
  • EUR 210.00
  • 100 g
  • 25 g
  • 500 g
  • 5 g

oxalic acid

20-abx182613
  • EUR 17181.60
  • EUR 3834.00
  • EUR 11101.20
  • 10 g
  • 1 g
  • 5 g

Chenodeoxycholic acid

abx183934-100g 100 g
EUR 276

Cholic acid

abx183940-100g 100 g
EUR 360

Cyclopropylboronic Acid

20-abx183964
  • EUR 710.40
  • EUR 360.00
  • EUR 243.60
  • 100 g
  • 25 g
  • 5 g

Diclofenac acid

20-abx183982
  • EUR 343.20
  • EUR 243.60
  • 25 g
  • 5 g

Heptafluorobutyric acid

20-abx184109
  • EUR 410.40
  • EUR 276.00
  • 100 g
  • 25 g

Hexadecanedioic acid

20-abx184111
  • EUR 1078.80
  • EUR 477.60
  • EUR 276.00
  • 100 g
  • 25 g
  • 5 g

Nipecotic acid

20-abx184279
  • EUR 292.80
  • EUR 226.80
  • EUR 243.60
  • EUR 577.20
  • 100 g
  • 10 g
  • 25 g
  • 500 g

Oleanolic acid

20-abx184292
  • EUR 627.60
  • EUR 526.80
  • EUR 1813.20
  • 1 g
  • 250 mg
  • 5 g

Tetrachlorophthalic acid

abx184419-25g 25 g
EUR 260.4

Tetradecanedioic acid

20-abx184421
  • EUR 243.60
  • EUR 510.00
  • EUR 309.60
  • 1 g
  • 25 g
  • 5 g

Vanillic acid

abx184472-500g 500 g
EUR 493.2

Zoledronic acid

20-abx184486
  • EUR 944.40
  • EUR 444.00
  • 100 g
  • 25 g

Nitrilotriacetic acid

20-abx184498
  • EUR 243.60
  • EUR 326.40
  • 100 g
  • 500 g

Cyclohexanepropionic acid

abx184664-500ml 500 ml
EUR 844.8

Deoxycholic acid

20-abx184668
  • EUR 326.40
  • EUR 243.60
  • EUR 777.60
  • 100 g
  • 25 g
  • 500 g

Mefenamic acid

abx184722-100g 100 g
EUR 444

Propionic acid

abx184763-5g 5 g
EUR 226.8

Tricarballylic acid

20-abx184792
  • EUR 744.00
  • EUR 376.80
  • EUR 260.40
  • 100 g
  • 25 g
  • 5 g

Trifluoromethanesulfonic acid

abx184793-500g 500 g
EUR 460.8

Benzoic acid

20-abx184806
  • EUR 243.60
  • EUR 210.00
  • EUR 343.20
  • 100 g
  • 25 g
  • 500 g

Phthalic acid

20-abx184816
  • EUR 292.80
  • EUR 243.60
  • 100 g
  • 25 g

Abscisic Acid

abx188577-1g 1 g
EUR 477.6

Arachidic Acid

abx188594-100g 100 g
EUR 477.6

Behenic Acid

abx188604-1kg 1 kg
EUR 427.2

Benzylboronic Acid

20-abx188610
  • EUR 427.20
  • EUR 878.40
  • 1 g
  • 5 g

Calconcarboxylic Acid

abx188633-1000g 1000 g
EUR 477.6

Linoleic Acid

abx188751-1000g 1000 g
EUR 526.8

Lithocholic Acid

abx188757-250g 250 g
EUR 961.2

Nonadecanedioic Acid

abx188823-25g 25 g
EUR 1629.6

Oxalacetic Acid

abx188826-250g 250 g
EUR 1996.8

Phenylphosphinic Acid

abx188837-1000g 1000 g
EUR 360

Polylactic Acid

abx188847-100g 100 g
EUR 727.2

Shikimic Acid

abx188877-500g 500 g
EUR 627.6

Succinamic Acid

abx188891-10g 10 g
EUR 410.4

Acid pyruvate

abx185349-500g 500 g
EUR 393.6

Angelic acid

20-abx185352
  • EUR 427.20
  • EUR 878.40
  • 1 g
  • 5 g

Diphenylacetic acid

20-abx185398
  • EUR 292.80
  • EUR 376.80
  • EUR 243.60
  • EUR 493.20
  • 100 g
  • 250 g
  • 25 g
  • 500 g

Folic acid

20-abx185440
  • EUR 360.00
  • EUR 243.60
  • EUR 744.00
  • 100 g
  • 25 g
  • 500 g

Niflumic Acid

20-abx185520
  • EUR 326.40
  • EUR 828.00
  • EUR 260.40
  • EUR 543.60
  • 100 g
  • 1 kg
  • 25 g
  • 500 g

Nonadecanoic acid

20-abx185524
  • EUR 594.00
  • EUR 276.00
  • 25 g
  • 5 g

Suberic acid

20-abx185569
  • EUR 610.80
  • EUR 444.00
  • 1 kg
  • 500 g

Butylboronic Acid

20-abx185847
  • EUR 460.80
  • EUR 210.00
  • EUR 292.80
  • EUR 226.80
  • 100 g
  • 1 g
  • 25 g
  • 5 g

Methoxyacetic acid

20-abx185865
  • EUR 243.60
  • EUR 526.80
  • 25 g
  • 500 g

Pentadecanedioic acid

20-abx185876
  • EUR 627.60
  • EUR 276.00
  • EUR 444.00
  • 10 g
  • 1 g
  • 5 g

Phenethylboronic Acid

20-abx185877
  • EUR 844.80
  • EUR 226.80
  • EUR 376.80
  • EUR 260.40
  • 100 g
  • 1 g
  • 25 g
  • 5 g

Lysophosphatidic Acid

20-abx185984
  • EUR 1262.40
  • EUR 560.40
  • EUR 292.80
  • 100 mg
  • 25.5 mg
  • 5 mg

Chloroplatinic acid

abx186079-1g 1 g
EUR 292.8

Acrylic acid

20-abx186368
  • EUR 1245.60
  • EUR 309.60
  • 10 kg
  • 1 kg

Cyclopropanecarboxylic acid

abx186704-500g 500 g
EUR 309.6

Citric Acid

abx186745-5g 5 g
EUR 226.8

Caffeic Acid

abx187919-1kg 1 kg
EUR 760.8

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