September 23, 2021
ucidevcell
Pcr Kits / Reagents / Ria Kits / serum / Western Blot

Dewetting: From Physics to the Biology of Intoxicated Cells

Jocelynby Jocelyn

Dewetting: From Physics to the Biology of Intoxicated Cells

 Pathogenic micro organism colonize or disseminate into cells and tissues by inducing large-scale remodeling of host membranes. The bodily phenomena underpinning these big membrane extension and deformation are poorly understood. Invasive strategies of pathogens have been simply recently enriched by the define of a spectacular mode of opening of huge transendothelial cell macroaperture (TEM) tunnels correlated to the dissemination of EDIN-producing strains of Staphylococcus aureus by means of a hematogenous route or to the induction of gelatinous edema triggered by the edema toxin from Bacillus anthracis.

Remarkably, these extraordinarily dynamic tunnels shut shortly after they attain a maximal measurement. Opening and closure of TEMs in cells lasts for hours with out inducing endothelial cell demise. Multidisciplinary analysis have started to produce a broader perspective of every the molecular determinants controlling cytoskeleton group at newly curved membranes generated by the opening of TEMs and the bodily processes controlling the dynamics of these tunnels.

Proper right here we speak in regards to the analogy between the opening of TEM tunnels and the bodily concepts of dewetting, stemming from a parallel between membrane stress and ground stress. This analogy provides a broad framework to analysis biophysical constraints in cell membrane dynamics and their diversion by positive invasive microbial brokers

Present advances in myeloid-derived suppressor cell biology

 

In latest occasions, discovering out the place of myeloid-derived suppressor cells (MDSCs) in numerous pathological inflammatory conditions has become a very energetic evaluation area. Although the place of MDSCs in most cancers is relatively successfully established, their place in non-cancerous pathological conditions stays in its infancy resulting in rather a lot confusion. Our targets on this overview are to cope with some present advances in MDSC evaluation in order to lower such confusion and to produce an notion into their function inside the context of various illnesses.

The following issues is perhaps significantly centered upon:

(1) definition and characterization of MDSCs;

(2) whether or not or not all MDSC populations embrace immature cells;

(3) technical factors in MDSC isolation, estimation and characterization;

(4) the origin of MDSCs and their anatomical distribution in effectively being and sickness;

(5) mediators of MDSC development and accumulation;

(6) parts that determine the expansion of 1 MDSC inhabitants over the other;

(7) the Yin and Yang roles of MDSCs. Moreover, the capabilities of MDSCs is perhaps addressed all by the textual content material.

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AIFL Blocking Peptide
AF9005-BP 1mg
EUR 195
AMPKgamma2 Blocking Peptide
AF9006-BP 1mg
EUR 195
ANKRD20 Blocking Peptide
AF9008-BP 1mg
EUR 195
APOBEC3A Blocking Peptide
AF9009-BP 1mg
EUR 195
ApoOL Blocking Peptide
AF9010-BP 1mg
EUR 195
ARHGAP1 Blocking Peptide
AF9011-BP 1mg
EUR 195
ARHGAP22 Blocking Peptide
AF9012-BP 1mg
EUR 195
ARHGEF19 Blocking Peptide
AF9013-BP 1mg
EUR 195
ARMCX1 Blocking Peptide
AF9014-BP 1mg
EUR 195
Arrdc1 Blocking Peptide
AF9016-BP 1mg
EUR 195
ARRDC2 Blocking Peptide
AF9017-BP 1mg
EUR 195
Arrdc4 Blocking Peptide
AF9018-BP 1mg
EUR 195
ASF1B Blocking Peptide
AF9022-BP 1mg
EUR 195
BAM32 Blocking Peptide
AF9023-BP 1mg
EUR 195
BEGAIN Blocking Peptide
AF9024-BP 1mg
EUR 195
BRD3 Blocking Peptide
AF9025-BP 1mg
EUR 195
BTBD6 Blocking Peptide
AF9026-BP 1mg
EUR 195
Cables2 Blocking Peptide
AF9029-BP 1mg
EUR 195
CaMKIbeta Blocking Peptide
AF9031-BP 1mg
EUR 195
CAS Blocking Peptide
AF9032-BP 1mg
EUR 195
CD158f2 Blocking Peptide
AF9037-BP 1mg
EUR 195
CD32 Blocking Peptide
AF9038-BP 1mg
EUR 195
Cdc16 Blocking Peptide
AF9039-BP 1mg
EUR 195
Centrobin Blocking Peptide
AF9040-BP 1mg
EUR 195
CEP152 Blocking Peptide
AF9041-BP 1mg
EUR 195
CMTM4 Blocking Peptide
AF9042-BP 1mg
EUR 195
CNOT2 Blocking Peptide
AF9043-BP 1mg
EUR 195
COL19A1 Blocking Peptide
AF9044-BP 1mg
EUR 195
COL4A6 Blocking Peptide
AF9045-BP 1mg
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COL5A3 Blocking Peptide
AF9046-BP 1mg
EUR 195
CRSP130 Blocking Peptide
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CYB561D1 Blocking Peptide
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CYP4F2 Blocking Peptide
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Eg5 Blocking Peptide
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Eps8L3 Blocking Peptide
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eRF3a Blocking Peptide
AF9062-BP 1mg
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ETL Blocking Peptide
AF9063-BP 1mg
EUR 195
FAM80B Blocking Peptide
AF9064-BP 1mg
EUR 195
FBP3 Blocking Peptide
AF9065-BP 1mg
EUR 195
FoxR1 Blocking Peptide
AF9067-BP 1mg
EUR 195
GAAP Blocking Peptide
AF9068-BP 1mg
EUR 195
GALR3 Blocking Peptide
AF9069-BP 1mg
EUR 195
GAS3 Blocking Peptide
AF9070-BP 1mg
EUR 195
GBP4 Blocking Peptide
AF9071-BP 1mg
EUR 195
GPR124 Blocking Peptide
AF9073-BP 1mg
EUR 195
GPR139 Blocking Peptide
AF9074-BP 1mg
EUR 195
GPR41 Blocking Peptide
AF9075-BP 1mg
EUR 195
GPR50 Blocking Peptide
AF9076-BP 1mg
EUR 195
GPRC5C Blocking Peptide
AF9077-BP 1mg
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Grap Blocking Peptide
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GRB10 Blocking Peptide
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GRIN2 Blocking Peptide
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EUR 195
GS28 Blocking Peptide
AF9082-BP 1mg
EUR 195
HABP2 Blocking Peptide
AF9083-BP 1mg
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HORMAD1 Blocking Peptide
AF9088-BP 1mg
EUR 195
HoxD10 Blocking Peptide
AF9089-BP 1mg
EUR 195
HoxD8 Blocking Peptide
AF9090-BP 1mg
EUR 195
HRT2 Blocking Peptide
AF9092-BP 1mg
EUR 195
INTS2 Blocking Peptide
AF9098-BP 1mg
EUR 195
KCNT1 Blocking Peptide
AF9099-BP 1mg
EUR 195
KIF13B Blocking Peptide
AF9100-BP 1mg
EUR 195
KIR3.1 Blocking Peptide
AF9101-BP 1mg
EUR 195
KIR3.4 Blocking Peptide
AF9102-BP 1mg
EUR 195
LHR Blocking Peptide
AF9104-BP 1mg
EUR 195
LONP2 Blocking Peptide
AF9105-BP 1mg
EUR 195
LRP10 Blocking Peptide
AF9106-BP 1mg
EUR 195
LUC7L2 Blocking Peptide
AF9107-BP 1mg
EUR 195
Matriptase Blocking Peptide
AF9109-BP 1mg
EUR 195
MCT12 Blocking Peptide
AF9110-BP 1mg
EUR 195
ME2 Blocking Peptide
AF9111-BP 1mg
EUR 195
MINK1 Blocking Peptide
AF9112-BP 1mg
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Mob3C Blocking Peptide
AF9114-BP 1mg
EUR 195
MPP1 Blocking Peptide
AF9115-BP 1mg
EUR 195
MRCKbeta Blocking Peptide
AF9116-BP 1mg
EUR 195
MRGF Blocking Peptide
AF9117-BP 1mg
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NDUFS5 Blocking Peptide
AF9124-BP 1mg
EUR 195
Nek9 Blocking Peptide
AF9125-BP 1mg
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AF9128-BP 1mg
EUR 195
NFRKB Blocking Peptide
AF9129-BP 1mg
EUR 195
Nicalin Blocking Peptide
AF9130-BP 1mg
EUR 195
Nidogen Blocking Peptide
AF9131-BP 1mg
EUR 195
NIPA Blocking Peptide
AF9132-BP 1mg
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NMUR1 Blocking Peptide
AF9133-BP 1mg
EUR 195
Nox3 Blocking Peptide
AF9134-BP 1mg
EUR 195
NRIP3 Blocking Peptide
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EUR 195
OMG Blocking Peptide
AF9146-BP 1mg
EUR 195
OTUB2 Blocking Peptide
AF9147-BP 1mg
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Oxr1 Blocking Peptide
AF9148-BP 1mg
EUR 195
PDE10A Blocking Peptide
AF9150-BP 1mg
EUR 195
PEG3 Blocking Peptide
AF9152-BP 1mg
EUR 195
Peropsin Blocking Peptide
AF9153-BP 1mg
EUR 195
PHF3 Blocking Peptide
AF9154-BP 1mg
EUR 195
PHKB Blocking Peptide
AF9156-BP 1mg
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PIG3 Blocking Peptide
AF9159-BP 1mg
EUR 195
PIPOX Blocking Peptide
AF9160-BP 1mg
EUR 195
PLA1A Blocking Peptide
AF9162-BP 1mg
EUR 195
Pmp24 Blocking Peptide
AF9163-BP 1mg
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PNPase Blocking Peptide
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POLR3B Blocking Peptide
AF9165-BP 1mg
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POLR3E Blocking Peptide
AF9166-BP 1mg
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PRPF31 Blocking Peptide
AF9169-BP 1mg
EUR 195
QSK Blocking Peptide
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RAB3IP Blocking Peptide
AF9176-BP 1mg
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Rabr Blocking Peptide
AF9177-BP 1mg
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RBM34 Blocking Peptide
AF9179-BP 1mg
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RCC2 Blocking Peptide
AF9180-BP 1mg
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RFX3 Blocking Peptide
AF9181-BP 1mg
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AF9186-BP 1mg
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AF9191-BP 1mg
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SH3BGR Blocking Peptide
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Sin3B Blocking Peptide
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StIp1 Blocking Peptide
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TAB182 Blocking Peptide
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MRGPRX2 indicators its significance in cutaneous mast cell biology: Does MRGPRX2 be part of mast cells and atopic dermatitis?

 

The invention of MRGPRX2 marks a necessary change in MC biology, explaining non-IgE-mediated scientific phenomena relying on MCs. As receptor for quite a few remedy, MRGPRX2 is important to drug-induced hypersensitivity.

Nonetheless, not solely remedy, however moreover endogenous mediators like neuropeptides and host safety peptides activate MRGPRX2, suggesting its broad affect in cutaneous pathophysiology.

Proper right here, we give a brief overview of MRGPRX2 and its regulation by microenvironmental stimuli, which assist MCs and shall be altered in pores and pores and skin points, and briefly contact on the purposeful packages elicited by MRGPRX2 ligation. Analysis in Mrgprb2-deficient mice (the murine ortholog) help illuminate MRGPRX2’s function in effectively being and sickness.

Present advances on this model assist the long-suspected operational unit between MCs and nerves, with MRGPRX2 being an vital component. Based on the restricted proof for a big contribution of FcεRI/IgE-activated MCs to atopic dermatitis (AD), we develop the hypothesis that MRGPRX2 constitutes the missing hyperlink connecting MCs and AD, a minimum of in chosen endotypes.

Help comes from the multifold changes inside the MC-neuronal system of AD pores and pores and skin (e.g. bigger density of MCs and nearer connections between MCs and nerves, elevated PAR-2/Substance P).

We theorize that these deregulations suffice to impress AD, nonetheless exterior triggers, numerous which activating MRGPRX2 themselves (e.g. Staphylococcus aureus) extra feed into the loop. Itch, most likely probably the most burdensome hallmark of AD, is usually non-histaminergic nonetheless tryptase-dependent, and tryptase is preferentially launched upon MRGPRX2 activation. On account of MRGPRX2 is a very energetic evaluation space, a couple of of the current gaps are susceptible to be closed shortly.

Non-Muscle Myosin II in Axonal Cell Biology: From the Growth Cone to the Axon Preliminary Part

 

By binding to actin filaments, non-muscle myosin II (NMII) generates actomyosin networks that preserve distinctive contractile properties. Their dynamic nature is vital for neuronal biology along with the establishment of polarity, progress cone formation and motility, axon progress all through enchancment (and axon regeneration inside the grownup), radial and longitudinal axonal stress, and synapse formation and efficiency.

On this overview, we speak in regards to the current information on the spatial distribution and efficiency of the actomyosin cytoskeleton in quite a few axonal compartments.

We highlight a couple of of the plain contradictions and open questions inside the space, along with the place of NMII inside the regulation of axon progress and regeneration, the possibility that NMII structural affiliation alongside the axon shaft would possibly administration every radial and longitudinal contractility, and the mechanism and purposeful goal underlying NMII enrichment inside the axon preliminary part.

With the advances in reside cell imaging and super choice microscopy, it is anticipated that inside the near future the spatial distribution of NMII inside the axon, and the mechanisms by which it participates in axonal biology is perhaps extra untangled.

D-Glucuronic acid, free acid
GB0482 5g
EUR 155.16
  • Product category: Biochemicals/Carbohydrates/Sugars

DL-Maleic acid (Toxilic acid)
MA0333 250g
EUR 64.5
  • Product category: Biochemicals/Biological Buffers/Buffer Related

Carnosic Acid
2075-25
EUR 436

Carnosic Acid
2075-5
EUR 147

Lithocholic acid
2187-1G
EUR 115

Lithocholic acid
2187-5G
EUR 272

Heptelidic Acid
2215-1000
EUR 490

Heptelidic Acid
2215-250
EUR 218

Retinoic acid
2218-250
EUR 338

Retinoic acid
2218-50
EUR 126

Kainic acid
2279-25
EUR 381

Kainic acid
2279-5
EUR 142

Caffeic acid
2303-250
EUR 196

Caffeic acid
2303-50
EUR 98

(+)-Abscisic acid
2543-1
EUR 120

(+)-Abscisic acid
2543-5
EUR 316

Itaconic acid
2576-1G
EUR 120

Itaconic acid
2576-5G
EUR 240

Gambogic acid
2785-25
EUR 544

Gambogic acid
2785-5
EUR 175

Chenodeoxycholic acid
2831-1G
EUR 120

Chenodeoxycholic acid
2831-25G
EUR 479

Chenodeoxycholic acid
2831-5G
EUR 185

Anacardic Acid
A160-10MG 10mg
EUR 120

Anacardic Acid
A160-250MG 250mg
EUR 249

Asterric Acid
A132-1MG 1 mg
EUR 261

Asterric Acid
A132-5MG 5 mg
EUR 839

Zoledronic Acid
A1352-100 100 mg
EUR 224
Description: Zoledronic acid, one of the most potent nitrogen-containing bisphosphonates, induces anti-proliferative and apoptotic effects on multiple myeloma cell lines in vitro by activating protein kinase C. Zoledronic acid also inhibits proliferation of human foet

Zoledronic Acid
A1352-25 25 mg
EUR 108
Description: Zoledronic acid, one of the most potent nitrogen-containing bisphosphonates, induces anti-proliferative and apoptotic effects on multiple myeloma cell lines in vitro by activating protein kinase C. Zoledronic acid also inhibits proliferation of human foet

Zoledronic Acid
A1352-5.1 10 mM (in 1mL DMSO)
EUR 108
Description: Zoledronic acid, one of the most potent nitrogen-containing bisphosphonates, induces anti-proliferative and apoptotic effects on multiple myeloma cell lines in vitro by activating protein kinase C. Zoledronic acid also inhibits proliferation of human foet

Arachidonic Acid
1505-100
EUR 169

Aurintricarboxylic acid
1506-1000
EUR 137

Okadaic acid
1543-025
EUR 157

Okadaic acid
1543-100
EUR 316

Betulinic acid
1552-100
EUR 375

Betulinic acid
1552-25
EUR 142

Oleanolic Acid
1731-100
EUR 115

Oleanolic Acid
1731-500
EUR 332

Rosmarinic Acid
1843-250
EUR 229

Rosmarinic Acid
1843-50
EUR 115

Anacardic Acid
1849-25
EUR 370

Anacardic Acid
1849-5
EUR 147

Mycophenolic Acid
1882-250
EUR 294

Mycophenolic Acid
1882-50
EUR 115

ICG acid
189 5 mg
EUR 219
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12171501

Pressinoic Acid
5-01806 4 x 5mg Ask for price

MB acid
40076 5MG
EUR 320
Description: Minimum order quantity: 1 unit of 5MG

Niflumic acid
B1530-5.1 10 mM (in 1mL DMSO)
EUR 108
Description: Niflumic acid, a Ca2+-activated Cl- channel blocker, is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.Niflumic acid, an inhibitor of calcium-activated chloride currents. Niflumic acid does not block directly calciu

Niflumic acid
B1530-50 50 mg
EUR 128
Description: Niflumic acid, a Ca2+-activated Cl- channel blocker, is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.Niflumic acid, an inhibitor of calcium-activated chloride currents. Niflumic acid does not block directly calciu

Niflumic acid
B1530-S Evaluation Sample
EUR 81
Description: Niflumic acid, a Ca2+-activated Cl- channel blocker, is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.Niflumic acid, an inhibitor of calcium-activated chloride currents. Niflumic acid does not block directly calciu

Benzoic Acid
B1676-5.1 10 mM (in 1mL DMSO)
EUR 108
Description: Benzoic acid is a colorless crystalline solid and a simple aromatic carboxylic acid, used as a food preservative.

Benzoic Acid
B1676-50 50 mg
EUR 128
Description: Benzoic acid is a colorless crystalline solid and a simple aromatic carboxylic acid, used as a food preservative.

Clofibric Acid
B1711-5.1 10 mM (in 1mL DMSO)
EUR 108
Description: Clofibric acid is a PPAR? agonist and hypolipidemic agent.

Clofibric Acid
B1711-50 50 mg
EUR 128
Description: Clofibric acid is a PPAR? agonist and hypolipidemic agent.

Flufenamic acid
B1760-100000 100 g
EUR 187
Description: Flufenamic acid

Flufenamic acid
B1760-250000 250 g
EUR 325
Description: Flufenamic acid

Flufenamic acid
B1760-50000 50 g
EUR 125
Description: Flufenamic acid

Tranexamic Acid
B1858-10000 10 g
EUR 142
Description: Tranexamic acid (Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.

Tranexamic Acid
B1858-5.1 10 mM (in 1mL DMSO)
EUR 108
Description: Tranexamic acid (Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.

Tranexamic Acid
B1858-50 50 mg
EUR 96
Description: Tranexamic acid (Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.

Tranexamic Acid
B1858-5000 5 g
EUR 108
Description: Tranexamic acid (Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.

Tropodithietic Acid
B1867-1
EUR 251

Oseltamivir Acid
B1886-1
EUR 131

Oseltamivir Acid
B1886-5
EUR 349

Obeticholic Acid
B1898-25
EUR 381

Obeticholic Acid
B1898-5
EUR 142

Chenodeoxycholic Acid
B1908-100 100 mg
EUR 96
Description: Chenodeoxycholic Acid (CDCA), is a hydrophobic primary bile acid that activates nuclear receptors(FXR) involved in cholesterol metabolism.

Chenodeoxycholic Acid
B1908-1000 1 g
EUR 108
Description: Chenodeoxycholic Acid (CDCA), is a hydrophobic primary bile acid that activates nuclear receptors(FXR) involved in cholesterol metabolism.

Chenodeoxycholic Acid
B1908-5.1 10 mM (in 1mL DMSO)
EUR 108
Description: Chenodeoxycholic Acid (CDCA), is a hydrophobic primary bile acid that activates nuclear receptors(FXR) involved in cholesterol metabolism.

Chenodeoxycholic Acid
B1908-5000 5 g
EUR 224
Description: Chenodeoxycholic Acid (CDCA), is a hydrophobic primary bile acid that activates nuclear receptors(FXR) involved in cholesterol metabolism.

Bempedoic acid
B1913-25
EUR 544

Bempedoic acid
B1913-5
EUR 175

Cyclamic acid
B1921-5.1 10 mM (in 1mL DMSO)
EUR 108
Description: Cyclamic acid in the form of its sodium or calcium salt is one of the most widely used artificial sweeteners.

Cyclamic acid
B1921-50 50 mg
EUR 128
Description: Cyclamic acid in the form of its sodium or calcium salt is one of the most widely used artificial sweeteners.

Cyclamic acid
B1921-S Evaluation Sample
EUR 81
Description: Cyclamic acid in the form of its sodium or calcium salt is one of the most widely used artificial sweeteners.

Mycophenolic acid
B1981-5.1 10 mM (in 1mL DMSO)
EUR 108
Description: Mycophenolic acid

Mycophenolic acid
B1981-50 50 mg
EUR 128
Description: Mycophenolic acid

Mycophenolic acid
B1981-S Evaluation Sample
EUR 81
Description: Mycophenolic acid

Nalidixic acid
B1985-5.1 10 mM (in 1mL DMSO)
EUR 108
Description: Nalidixic acid

Nalidixic acid
B1985-50 50 mg
EUR 128
Description: Nalidixic acid

Nalidixic acid
B1985-S Evaluation Sample
EUR 81
Description: Nalidixic acid

Nicotinic Acid
B1987-100000 100 g
EUR 108
Description: Niacin (Vitamin B3) is a water-soluble vitamin and is part of the vitamin B group.

Nicotinic Acid
B1987-5.1 10 mM (in 1mL DMSO)
EUR 108
Description: Niacin (Vitamin B3) is a water-soluble vitamin and is part of the vitamin B group.

Nicotinic Acid
B1987-50 50 mg
EUR 96
Description: Niacin (Vitamin B3) is a water-soluble vitamin and is part of the vitamin B group.

Nicotinic Acid
B1987-500000 500 g
EUR 224
Description: Niacin (Vitamin B3) is a water-soluble vitamin and is part of the vitamin B group.

Aspterric acid
B2233-1
EUR 370

Aspterric acid
B2233-5
EUR 1240

Gibberellic acid
B2234-1G
EUR 120

Gibberellic acid
B2234-5G
EUR 327

Fusidic acid
B2392-100
EUR 120

Fusidic acid
B2392-500
EUR 240

Carglumic acid
B2447-10
EUR 109

Carglumic acid
B2447-50
EUR 229

Eicosapentaenoic Acid
B3464-100 100 mg
EUR 116

Obeticholic Acid
B4888-100 100 mg
EUR 595
Description: Obeticholic Acid (6alpha-ethyl-chenodeoxycholic acid, 6-ECDCA, INT-747) is a potent and selective agonist of FXR with EC50 value of 99 nM [1].

Obeticholic Acid
B4888-25 25 mg
EUR 282
Description: Obeticholic Acid (6alpha-ethyl-chenodeoxycholic acid, 6-ECDCA, INT-747) is a potent and selective agonist of FXR with EC50 value of 99 nM [1].

Obeticholic Acid
B4888-5 5 mg
EUR 108
Description: Obeticholic Acid (6alpha-ethyl-chenodeoxycholic acid, 6-ECDCA, INT-747) is a potent and selective agonist of FXR with EC50 value of 99 nM [1].

Obeticholic Acid
B4888-5.1 10 mM (in 1mL DMSO)
EUR 113
Description: Obeticholic Acid (6alpha-ethyl-chenodeoxycholic acid, 6-ECDCA, INT-747) is a potent and selective agonist of FXR with EC50 value of 99 nM [1].

Salicylic acid
B1092-10000 10 g
EUR 119
Description: Salicylic acid is a natural product extract from Willow bark, well known as an antiinflammatory inhibitor of cyclooxygenase activity.

Salicylic acid
B1092-5.1 10 mM (in 1mL DMSO)
EUR 108
Description: Salicylic acid is a natural product extract from Willow bark, well known as an antiinflammatory inhibitor of cyclooxygenase activity.

Salicylic acid
B1092-50000 50 g
EUR 142
Description: Salicylic acid is a natural product extract from Willow bark, well known as an antiinflammatory inhibitor of cyclooxygenase activity.

Orotic acid
B1147-5.1 10 mM (in 1mL DMSO)
EUR 108
Description: Orotic acid (OA) is an intermediate in pyrimidine metabolism.

Orotic acid
B1147-500 500 mg
EUR 108
Description: Orotic acid (OA) is an intermediate in pyrimidine metabolism.

Ellagic Acid
B1154-100
EUR 109

Ellagic Acid
B1154-500
EUR 240

Valproic acid
B1251-10000 10 g
EUR 189
Description: Valproic acid is an inhibitor of HDAC1 with IC50 value of 0.4mM [1].Valproic acid (VPA) is a branched short-chain fatty acid. It is previously synthesized and used as an inert solvent of organic compounds.

Valproic acid
B1251-5.1 10 mM (in 1mL DMSO)
EUR 108
Description: Valproic acid is an inhibitor of HDAC1 with IC50 value of 0.4mM [1].Valproic acid (VPA) is a branched short-chain fatty acid. It is previously synthesized and used as an inert solvent of organic compounds.

Valproic acid
B1251-5000 5 g
EUR 142
Description: Valproic acid is an inhibitor of HDAC1 with IC50 value of 0.4mM [1].Valproic acid (VPA) is a branched short-chain fatty acid. It is previously synthesized and used as an inert solvent of organic compounds.

Mefenamic Acid
B1449-5.1 10 mM (in 1mL DMSO)
EUR 108
Description: Mefenamic acid is a non-steroidal anti-inflammatory agent, which is an inhibitor of cyclooxygenase.Mefenamic acid is a non-steroidal anti-inflammatory drug used to treat pain, including menstrual pain. It is typically prescribed for oral administration. M

Mefenamic Acid
B1449-50 50 mg
EUR 128
Description: Mefenamic acid is a non-steroidal anti-inflammatory agent, which is an inhibitor of cyclooxygenase.Mefenamic acid is a non-steroidal anti-inflammatory drug used to treat pain, including menstrual pain. It is typically prescribed for oral administration. M

Mefenamic Acid
B1449-S Evaluation Sample
EUR 81
Description: Mefenamic acid is a non-steroidal anti-inflammatory agent, which is an inhibitor of cyclooxygenase.Mefenamic acid is a non-steroidal anti-inflammatory drug used to treat pain, including menstrual pain. It is typically prescribed for oral administration. M

Tolfenamic Acid
B1455-5.1 10 mM (in 1mL DMSO)
EUR 108
Description: Tolfenamic acid (TA) is one of the class of non-steroidal anti-inflammatory drugs (NSAIDs).Tolfenamic acid is a NSAID. Tolfenamic acid treatment inhibited cell growth and induced apoptosis as measured by caspase activity and bioelectric impedance. Tolfena

Tolfenamic Acid
B1455-50 50 mg
EUR 102
Description: Tolfenamic acid (TA) is one of the class of non-steroidal anti-inflammatory drugs (NSAIDs).Tolfenamic acid is a NSAID. Tolfenamic acid treatment inhibited cell growth and induced apoptosis as measured by caspase activity and bioelectric impedance. Tolfena

Tolfenamic Acid
B1455-S Evaluation Sample
EUR 81
Description: Tolfenamic acid (TA) is one of the class of non-steroidal anti-inflammatory drugs (NSAIDs).Tolfenamic acid is a NSAID. Tolfenamic acid treatment inhibited cell growth and induced apoptosis as measured by caspase activity and bioelectric impedance. Tolfena

Grifolic acid
B5647-.5 500 µg
EUR 142

Grifolic acid
B5647-1 1 mg
EUR 203

Suberohydroxamic Acid
B5976-1000 1 g
EUR 241
Description: Suberohydroxamic Acid (Suberoyl bis-hydroxamic acid, SBHA) is an inhibitor of HDAC with ID50 values of 0.25 and 0.30 ?M for HDAC1 and HDAC3, respectively [1].

Suberohydroxamic Acid
B5976-5.1 10 mM (in 1mL DMSO)
EUR 108
Description: Suberohydroxamic Acid (Suberoyl bis-hydroxamic acid, SBHA) is an inhibitor of HDAC with ID50 values of 0.25 and 0.30 ?M for HDAC1 and HDAC3, respectively [1].

Suberohydroxamic Acid
B5976-500 500 mg
EUR 166
Description: Suberohydroxamic Acid (Suberoyl bis-hydroxamic acid, SBHA) is an inhibitor of HDAC with ID50 values of 0.25 and 0.30 ?M for HDAC1 and HDAC3, respectively [1].

Fenofibric acid
B6128-100 100 mg
EUR 128

Fenofibric acid
B6128-500 500 mg
EUR 290

Oxolinic acid
B6129-10000 10 g
EUR 206
Description: IC50: 4.3 ?M for dopamine uptakeOxolinic acid is a quinolone antibiotic inhibiting bacterial DNA gyrase.DNA gyrase, an enzyme within the class of topoisomerase, relieves strain while double-stranded DNA is being unwound by helicase.

Oxolinic acid
B6129-25000 25 g
EUR 398
Description: IC50: 4.3 ?M for dopamine uptakeOxolinic acid is a quinolone antibiotic inhibiting bacterial DNA gyrase.DNA gyrase, an enzyme within the class of topoisomerase, relieves strain while double-stranded DNA is being unwound by helicase.

Oxolinic acid
B6129-5000 5 g
EUR 137
Description: IC50: 4.3 ?M for dopamine uptakeOxolinic acid is a quinolone antibiotic inhibiting bacterial DNA gyrase.DNA gyrase, an enzyme within the class of topoisomerase, relieves strain while double-stranded DNA is being unwound by helicase.

Lauric Acid
B6155-250000 250 g
EUR 119
Description: Lauric acid, a saturated medium-chain fatty acid with a 12-carbon backbone, is naturally found in various plant and animal fats and oils, which is a major component of palm kernel oil and coconut oil.

Dihydrokainic acid
B6208-1 1 mg
EUR 187

Dihydrokainic acid
B6208-10 10 mg
EUR 334

Dihydrokainic acid
B6208-50 50 mg
EUR 1243

Homoquinolinic acid
B6223-10 10 mg
EUR 357

Homoquinolinic acid
B6223-50 50 mg
EUR 1340

Kainic acid
B6226-1 1 mg
EUR 171
Description: Kainic acid is a selective agonist of kainate receptor [1]. Kainate receptor is an ionotropic receptor that responds to glutamate.

Kainic acid
B6226-10 10 mg
EUR 308
Description: Kainic acid is a selective agonist of kainate receptor [1]. Kainate receptor is an ionotropic receptor that responds to glutamate.

Kainic acid
B6226-50 50 mg
EUR 1136
Description: Kainic acid is a selective agonist of kainate receptor [1]. Kainate receptor is an ionotropic receptor that responds to glutamate.

Kynurenic acid
B6227-5000 5 g
EUR 196

Quinolinic acid
B6228-1000 1 g
EUR 132

Quinolinic acid
B6228-5.1 10 mM (in 1mL DMSO)
EUR 108

(±)-Nipecotic acid
B6231-100 100 mg
EUR 177

Domoic acid
B6241-1 1 mg
EUR 350

Ibotenic acid
B6246-1 1 mg
EUR 115

Ibotenic acid
B6246-25 25 mg
EUR 1276

Ibotenic acid
B6246-5 5 mg
EUR 328

Spaglumic acid
B6288-10 10 mg
EUR 139

Spaglumic acid
B6288-50 50 mg
EUR 231

Folic Acid
AT062 1mg
EUR 945

Ferulic Acid
AT130 1mg
EUR 1790

Benzoic Acid
AT153 1mg
EUR 1368

Trichlorophenoxyacetic Acid
AT169 1mg
EUR 1368

Tenuazonic acid
AT183 1mg
EUR 1114

Glycochenodeoxycholic acid
AT216 1mg
EUR 1114

Arsanilic acid
AT255 1mg
EUR 1368

Gibberellic acid
AT268 1mg
EUR 1368

Dihydroaeruginoic acid
D052-25MG 25 mg
EUR 670

Dihydroaeruginoic acid
D052-5MG 5 mg
EUR 213

Dipicolinic acid
D084-25MG 25 mg
EUR 238

Dipicolinic acid
D084-5MG 5 mg
EUR 89

?-Glycyrrhetinic acid
9586-1G
EUR 120

Abscisic Acid
abx188577-1g 1 g
EUR 398
  • Shipped within 1-2 weeks.

Arachidic Acid
abx188594-100g 100 g
EUR 398
  • Shipped within 1-2 weeks.

Behenic Acid
abx188604-1kg 1 kg
EUR 356
  • Shipped within 1-2 weeks.

Benzylboronic Acid
20-abx188610
  • EUR 356.00
  • EUR 732.00
  • 1 g
  • 5 g
  • Shipped within 1-2 weeks.

Calconcarboxylic Acid
abx188633-1000g 1000 g
EUR 398
  • Shipped within 1-2 weeks.

Jocelyn

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