Regenerative Remedy in Cardiovascular Ischemic Illness: Biology, Signaling Pathways, and Epigenetics

The State of Artwork of Regenerative Remedy in Cardiovascular Ischemic Illness: Biology, Signaling Pathways, and Epigenetics of Endothelial Progenitor Cells

Ischemic coronary heart illness is presently a serious reason for mortality and morbidity worldwide. Nonetheless, the precise therapeutic situation doesn’t goal myocardial cell regeneration and consequently, the development towards the late stage of power coronary heart failure is frequent. Endothelial progenitor cells (EPCs) are bone marrow-derived stem cells that contribute to the homeostasis of the endothelial wall in acute and power ischemic illness. Calcium modulation and different molecular pathways (NOTCH, VEGFR, and CXCR4) contribute to EPC proliferation and differentiation. The current evaluate supplies a abstract of EPC biology with a selected concentrate on the regulatory pathways of EPCs and describes promising functions for cardiovascular cell remedy. 

Understanding angiodiversity: insights from single cell biology

Blood vessels have lengthy been thought-about as passive conduits for delivering blood. Nevertheless, lately, cells of the vessel wall (endothelial cells, clean muscle cells and pericytes) have emerged as lively, extremely dynamic parts that orchestrate crosstalk between the circulation and organs. 

• Encompassing the entire physique and being specialised to the wants of distinct organs, it’s not shocking that vessel lining cells come in several flavours.
  
• There may be calibre-specific specialization (arteries, arterioles, capillaries, venules, veins), but in addition organ-specific heterogeneity in several microvascular beds (steady, discontinuous, sinusoidal).
  
• Latest technical advances within the discipline of single cell biology have enabled the profiling of hundreds of single cells and, therefore, have allowed for the molecular dissection of such angiodiversity, yielding a hitherto unparalleled stage of spatial and useful decision.
  
• Right here, we evaluate how these approaches have contributed to our understanding of angiodiversity.

PTPN1 Protein (Recombinant)
20-abx073070	Abbexa	EUR 230.00 EUR 2332.00 EUR 328.00	10 ug 1 mg 50 ug
Shipped within 5-10 working days.

PPM1A Protein (Recombinant)
20-abx073071	Abbexa	EUR 230.00 EUR 2332.00 EUR 328.00	10 ug 1 mg 50 ug
Shipped within 5-10 working days.

PTP4A3 Protein (Recombinant)
20-abx073078	Abbexa	EUR 230.00 EUR 2332.00 EUR 328.00	10 ug 1 mg 50 ug
Shipped within 5-10 working days.

SKP1 Protein (Recombinant)
20-abx073140	Abbexa	EUR 2861.00 EUR 328.00 EUR 230.00	1 mg 25 ug 5 ug
Shipped within 5-10 working days.

Ketohexokinase Protein (Recombinant)
20-abx073142	Abbexa	EUR 2861.00 EUR 328.00 EUR 230.00	1 mg 25 ug 5 ug
Shipped within 5-10 working days.

NGAL Protein (Recombinant)
20-abx073150	Abbexa	EUR 328.00 EUR 3084.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

DDAH1 Protein (Recombinant)
20-abx073166	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

PTP4A1 Protein (Recombinant)
20-abx073184	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

PPP3R1 Protein (Recombinant)
20-abx073192	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

PPM1F Protein (Recombinant)
20-abx073211	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

PPME1 Protein (Recombinant)
20-abx073232	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

PPP4C Protein (Recombinant)
20-abx073279	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

ACAD8 Protein (Recombinant)
20-abx073280	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

ACAT2 Protein (Recombinant)
20-abx073281	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

RNASE3 Protein (Recombinant)
20-abx073373	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

MAPKAPK3 Protein (Recombinant)
20-abx073468	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

PRKAB2 Protein (Recombinant)
20-abx073469	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

ATF3 Protein (Recombinant)
20-abx073484	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

DYRK1A Protein (Recombinant)
20-abx073488	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

PTPN6 Protein (Recombinant)
20-abx073509	Abbexa	EUR 3530.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

NGAL Protein (Recombinant)
20-abx073513	Abbexa	EUR 3766.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

NGAL Protein (Recombinant)
20-abx073525	Abbexa	EUR 328.00 EUR 4281.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

PTPMT1 Protein (Recombinant)
20-abx073545	Abbexa	EUR 4490.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

PPP1R14A Protein (Recombinant)
20-abx073553	Abbexa	EUR 4490.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

PPP1R2 Protein (Recombinant)
20-abx073582	Abbexa	EUR 4490.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

PRKA1RA Protein (Recombinant)
20-abx073603	Abbexa	EUR 4615.00 EUR 230.00 EUR 328.00	100 ug 1 µg 3 µg
Shipped within 5-10 working days.

PPARG Protein (Recombinant)
20-abx073662	Abbexa	EUR 328.00 EUR 5924.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

PPP3R2 Protein (Recombinant)
20-abx073701	Abbexa	EUR 6397.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

ACADL Protein (Recombinant)
20-abx073728	Abbexa	EUR 328.00 EUR 6397.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

ACADVL Protein (Recombinant)
20-abx073752	Abbexa	EUR 328.00 EUR 6397.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

ACADS Protein (Recombinant)
20-abx073767	Abbexa	EUR 328.00 EUR 6397.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

ACADM Protein (Recombinant)
20-abx073777	Abbexa	EUR 328.00 EUR 6397.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

ACADSB Protein (Recombinant)
20-abx073808	Abbexa	EUR 328.00 EUR 6397.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

PPP1R8 Protein (Recombinant)
20-abx073809	Abbexa	EUR 328.00 EUR 6397.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

ATF4 Protein (Recombinant)
20-abx073858	Abbexa	EUR 328.00 EUR 6397.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

CDK2 Protein (Recombinant)
20-abx073859	Abbexa	EUR 328.00 EUR 6397.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

FGFR1 Protein (Recombinant)
20-abx073878	Abbexa	EUR 328.00 EUR 6397.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

Ribokinase Protein (Recombinant)
20-abx073896	Abbexa	EUR 328.00 EUR 6397.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

ADK Protein (Recombinant)
20-abx073897	Abbexa	EUR 328.00 EUR 6397.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

PTP4A2 Protein (Recombinant)
20-abx073900	Abbexa	EUR 6397.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

PTPN7 Protein (Recombinant)
20-abx073941	Abbexa	EUR 230.00 EUR 1483.00 EUR 328.00	1 µg 50 ug 5 ug
Shipped within 5-10 working days.

PPP3CA Protein (Recombinant)
20-abx073950	Abbexa	EUR 230.00 EUR 1609.00 EUR 328.00	1 µg 50 ug 5 ug
Shipped within 5-10 working days.

PPP1CA Protein (Recombinant)
20-abx073956	Abbexa	EUR 230.00 EUR 1609.00 EUR 328.00	1 µg 50 ug 5 ug
Shipped within 5-10 working days.

ABHD14B Protein (Recombinant)
20-abx073961	Abbexa	EUR 230.00 EUR 1609.00 EUR 328.00	1 µg 50 ug 5 ug
Shipped within 5-10 working days.

PPP1CC Protein (Recombinant)
20-abx073968	Abbexa	EUR 1609.00 EUR 328.00 EUR 230.00	100 ug 10 ug 2 µg
Shipped within 5-10 working days.

PTPRC Protein (Recombinant)
20-abx073990	Abbexa	EUR 1609.00 EUR 328.00 EUR 230.00	100 ug 10 ug 2 µg
Shipped within 5-10 working days.

AMH Recombinant Protein
30R-3463	Fitzgerald	100 ug	EUR 1321
Description: Anti Mullerian Hormone Antigen, Recombinant

AMH Recombinant Protein
30R-3464	Fitzgerald	100 ug	EUR 1839
Description: Anti Mullerian Hormone Antigen, Recombinant

Recombinant Protein G
7-05935	CHI Scientific	1mg	Ask for price

Recombinant Protein G
7-05936	CHI Scientific	10mg	Ask for price

Recombinant Protein G
7-05937	CHI Scientific	100mg	Ask for price

Recombinant Protein A
DAG390	Creative Diagnostics	1g	EUR 1940

KIAA0513Human Recombinant Protein
PROTO60268	BosterBio	Regular: 10ug	EUR 317
Description: KIAA0513 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 424 amino acids (1-401 a.a) and having a molecular mass of 47.9kDa.;KIAA0513 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Batroxobin Recombinant Protein
PROTP04971	BosterBio	Regular: 10ug	EUR 317
Description: The Batroxobin Recombinant Protein, produced in yeast, is a single, glycosilated polypeptide chain containing 231 amino acids and having an Mw of approximately 28-33 kDa.

Lysostaphin Recombinant Protein
PROTP10547	BosterBio	Regular: 5mg	EUR 366
Description: Lysostaphin, an endopeptidase specific for the cell wall peptidoglycan of staphylococci, is an extremely potent anti-staphylococcal agent. Lysostaphin is used as a research and diagnostic tool. Because it lyses staphylococci efficiently, it is widely used when preparing staphylococcal DNA or other cellular components for genetic and biochemical studies and for the preparation of protoplasts for transformation. Preparation and analysis of bacterial DNA has become a powerful tool used by clinical and other microbiologists in epidemiological studies aimed at tracing sources of infection or bacterial contamination.;The Mw of lysostaphin is 26,921 (Recsei et al, PNAS 1987).

LIN7BHuman Recombinant Protein
PROTQ9HAP6	BosterBio	Regular: 10ug	EUR 317
Description: LIN7B Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 230 amino acids (1-207 a.a.) and having a molecular mass of 25.3kDa.;LIN7B is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Streptavidin Recombinant Protein
PROTP22629-2	BosterBio	Regular: 20mg	EUR 317
Description: Streptavidin Streptomyces Avidinii Recombinant produced in E.Coli. ;The molecular weight per tetramer is approximately 52kDa.

Staphylokinase Recombinant Protein
PROTP68802	BosterBio	Regular: 100ug	EUR 317
Description: Staphylokinase Recombinant produced in E.Coli is a non-glycosylated polypeptide chain containing 136 amino acids and having a molecular weight of 16kDa.;The Staphylokinase is purified by proprietary chromatographic techniques.

TIAL1Human Recombinant Protein
PROTQ01085	BosterBio	Regular: 20ug	EUR 317
Description: TIAL1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 398 amino acids (1-375 a.a) and having a molecular mass of 44.0kDa.TIAL1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Recombinant Coxsackievirus Protein
VAng-Lsx0074-inquire	Creative Biolabs	inquire	Ask for price
Description: Coxsackievirus antigen, recombinant protein from E. coli.

Recombinant EBV Protein
VAng-Lsx0108-inquire	Creative Biolabs	inquire	Ask for price
Description: EBV, recombinant protein from human cells.

Recombinant EBOV Protein
VAng-Lsx0136-1mg	Creative Biolabs	1 mg	EUR 1138
Description: EBOV, recombinant protein from E. coli.

Recombinant Hantavirus Protein
VAng-Lsx0152-100gEcoli	Creative Biolabs	100 µg (E. coli)	EUR 670
Description: Hantavirus, recombinant protein from E. coli.

Recombinant Hantavirus Protein
VAng-Lsx0152-1mgEcoli	Creative Biolabs	1 mg (E. coli)	EUR 3402
Description: Hantavirus, recombinant protein from E. coli.

Recombinant Hantavirus Protein
VAng-Lsx0152-500gEcoli	Creative Biolabs	500 µg (E. coli)	EUR 1787
Description: Hantavirus, recombinant protein from E. coli.

Recombinant RSV Protein
VAng-Lsx0448-inquire	Creative Biolabs	inquire	Ask for price
Description: RSV, recombinant protein from Hep-2 Cells.

Recombinant HBV Protein
VAng-Lsx0175-1mg	Creative Biolabs	1 mg	EUR 3470
Description: HBV, recombinant protein from E. coli.

Recombinant HDV Protein
VAng-Lsx0220-inquire	Creative Biolabs	inquire	Ask for price
Description: HDV, recombinant protein from E. coli.

Recombinant Rotavirus Protein
VAng-Lsx0471-inquire	Creative Biolabs	inquire	Ask for price
Description: RotaVirus, recombinant protein from MA 104 cells.

Recombinant SIV Protein
VAng-Lsx0493-inquire	Creative Biolabs	inquire	Ask for price
Description: Recombinant SIV p55- Strains: SIV mac 23g and SIV smH4 is glycosylated with N-linked sugars and produced using baculovirus vectors in insect cells.

Recombinant Echovirus Protein
VAng-Lsx0595-inquire	Creative Biolabs	inquire	Ask for price
Description: Echovirus, recombinant protein from E. coli.

STAG3L1 Recombinant Protein (Human) (Recombinant Tag)
RP030283	ABM	100 ug	Ask for price

STAG3L2 Recombinant Protein (Human) (Recombinant Tag)
RP030286	ABM	100 ug	Ask for price

STAG3L3 Recombinant Protein (Human) (Recombinant Tag)
RP030289	ABM	100 ug	Ask for price

STAG3L4 Recombinant Protein (Human) (Recombinant Tag)
RP030292	ABM	100 ug	Ask for price

TAGAP Recombinant Protein (Human) (Recombinant- Tag)
RP030880	ABM	100 ug	Ask for price

TAGLN Recombinant Protein (Human) (Recombinant- Tag)
RP030883	ABM	100 ug	Ask for price

TAGLN Recombinant Protein (Human) (Recombinant- Tag)
RP030886	ABM	100 ug	Ask for price

TAGLN2 Recombinant Protein (Human) (Recombinant Tag)
RP030889	ABM	100 ug	Ask for price

TAGLN2 Recombinant Protein (Human) (Recombinant Tag)
RP030892	ABM	100 ug	Ask for price

TAGLN3 Recombinant Protein (Human) (Recombinant Tag)
RP030895	ABM	100 ug	Ask for price

CTAG1A Recombinant Protein (Human) (Recombinant- Tag)
RP038332	ABM	100 ug	Ask for price

CTAG1B Recombinant Protein (Human) (Recombinant- Tag)
RP038335	ABM	100 ug	Ask for price

CTAGE5 Recombinant Protein (Human) (Recombinant- Tag)
RP038338	ABM	100 ug	Ask for price

TAGAP Recombinant Protein (Human) (Recombinant- Tag)
RP043930	ABM	100 ug	Ask for price

CTAGE3P Recombinant Protein (Human) (Recombinant Tag)
RP053400	ABM	100 ug	Ask for price

CTAGE4 Recombinant Protein (Human) (Recombinant- Tag)
RP053403	ABM	100 ug	Ask for price

CTAGE8 Recombinant Protein (Human) (Recombinant- Tag)
RP053409	ABM	100 ug	Ask for price

CTAGE9 Recombinant Protein (Human) (Recombinant- Tag)
RP053412	ABM	100 ug	Ask for price

CTAGE1 Recombinant Protein (Human) (Recombinant- Tag)
RP008266	ABM	100 ug	Ask for price

CTAGE5 Recombinant Protein (Human) (Recombinant- Tag)
RP008269	ABM	100 ug	Ask for price

CTAGE6P Recombinant Protein (Human) (Recombinant Tag)
RP008272	ABM	100 ug	Ask for price

CTAGEP Recombinant Protein (Human) (Recombinant- Tag)
RP008275	ABM	100 ug	Ask for price

TAGLN Recombinant Protein (Rat) (Recombinant- Tag)
RP232205	ABM	100 ug	Ask for price

TAGLN2 Recombinant Protein (Rat) (Recombinant Tag)
RP232208	ABM	100 ug	Ask for price

TAGLN3 Recombinant Protein (Rat) (Recombinant Tag)
RP232211	ABM	100 ug	Ask for price

TAGLN3 Recombinant Protein (Rat) (Recombinant Tag)
RP232214	ABM	100 ug	Ask for price

TAGAP Recombinant Protein (Mouse) (Recombinant- Tag)
RP177155	ABM	100 ug	Ask for price

Tagap1 Recombinant Protein (Mouse) (Recombinant Tag)
RP177158	ABM	100 ug	Ask for price

TAGLN Recombinant Protein (Mouse) (Recombinant- Tag)
RP177161	ABM	100 ug	Ask for price

TAGLN2 Recombinant Protein (Mouse) (Recombinant Tag)
RP177164	ABM	100 ug	Ask for price

TAGLN3 Recombinant Protein (Mouse) (Recombinant Tag)
RP177167	ABM	100 ug	Ask for price

CTAGE5 Recombinant Protein (Mouse) (Recombinant- Tag)
RP126449	ABM	100 ug	Ask for price

CTAGE5 Recombinant Protein (Mouse) (Recombinant- Tag)
RP126452	ABM	100 ug	Ask for price

CTAGE5 Recombinant Protein (Mouse) (Recombinant- Tag)
RP126455	ABM	100 ug	Ask for price

Protein Export Protein SecB Recombinant Protein
PROTP0AG86	BosterBio	Regular: 25ug	EUR 317
Description: Recombinant E.Coli SecB produced in E.Coli is a single, non-glycosylated polypeptide chain containing 155 amino acids and having a molecular mass of 17.2 kDa. SecB was over-expressed in E. coli and purified by conventional chromatography.

Recombinant Protein Export Protein SecB
7-06340	CHI Scientific	5µg	Ask for price

Recombinant Protein Export Protein SecB
7-06341	CHI Scientific	25µg	Ask for price

Recombinant Protein Export Protein SecB
7-06342	CHI Scientific	1mg	Ask for price

Zika NS1 Protein Recombinant Protein
PROTB5AHE9	BosterBio	Regular: 0.5mg	EUR 788
Description: The E.Coli derived Recombinant Zika NS1 protein (Strain: ZikaSPH2015) having an Mw of 45kDa is derived from the full length Zika NS1 protein. ;The Zika NS1 protein is fused to a 6xHis tag at C-terminus and purified by proprietary chromatographic technique.

p53 Protein Human Recombinant Protein
PROTP04637-1	BosterBio	Regular: 5ug	EUR 479
Description: p53 Human Recombinant full length produced in E.Coli is a non-glycosylated, polypeptide chain having a total Mw of 81kDa. p53 Human Recombinant is fused to GST tag and purified by proprietary chromatographic techniques.

PHF11 Protein Human Recombinant Protein
PROTQ9UIL8	BosterBio	Regular: 20ug	EUR 317
Description: PHF11 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 351 amino acids (1-331 a.a.) and having a molecular mass of 39.7kDa.;PHF11 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

BAD Protein Human Recombinant Protein
PROTQ92934	BosterBio	Regular: 5ug	EUR 479
Description: Bcl2 antagonist of cell death (BAD) Human Recombinant full length protein expressed in E.coli, shows a 51 kDa band on SDS-PAGE(Icluding GST tag). ;The BAD protein is purified by proprietary chromatographic techniques.

CTAG2 Recombinant Protein (Human) (Recombinant-P Tag)
RP053376	ABM	100 ug	Ask for price

CTAG2 Recombinant Protein (Rat) (Recombinant-P Tag)
RP196619	ABM	100 ug	Ask for price

CTAG2 Recombinant Protein (Mouse) (Recombinant-P Tag)
RP126446	ABM	100 ug	Ask for price

Disulfide Isomerase Protein (Recombinant)
20-abx073027	Abbexa	EUR 940.00 EUR 370.00 EUR 1428.00	0.5 mg 100 ug 1 mg
Shipped within 5-10 working days.

Phosphatase 1G Protein(Recombinant)
20-abx073051	Abbexa	EUR 230.00 EUR 2332.00 EUR 328.00	10 ug 1 mg 50 ug
Shipped within 5-10 working days.

Deoxythymidylate Kinase Protein (Recombinant)
20-abx073454	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

Pantothenate Kinase Protein (Recombinant)
20-abx073459	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

Cyclin-A2 Protein (Recombinant)
20-abx073464	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

Mevalonate Kinase Protein (Recombinant)
20-abx073473	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

E.coli Glucokinase Protein (Recombinant)
20-abx073476	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

Phosphomevalonate Kinase Protein (Recombinant)
20-abx073487	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

Cyclin-I Protein (Recombinant)
20-abx073492	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

Phosphoserine Phosphatase Protein (Recombinant)
20-abx073510	Abbexa	EUR 3530.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

Riboflavin Kinase Protein (Recombinant)
20-abx073520	Abbexa	EUR 3766.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

Galactokinase 1 Protein (Recombinant)
20-abx073596	Abbexa	EUR 4490.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

Deoxycytidine Kinase Protein (Recombinant)
20-abx073597	Abbexa	EUR 4490.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

Phosphofructokinase, Muscle Protein (Recombinant)
20-abx073602	Abbexa	EUR 4490.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

PKAr-1a Protein (Recombinant)
20-abx073605	Abbexa	EUR 4615.00 EUR 230.00 EUR 328.00	100 ug 1 µg 3 µg
Shipped within 5-10 working days.

Ribosomal Protein L12 (Recombinant)
20-abx073817	Abbexa	EUR 328.00 EUR 6397.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

Cyclin-B2 Protein (Recombinant)
20-abx073867	Abbexa	EUR 328.00 EUR 6397.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

Hexokinase-1 Protein (Recombinant)
20-abx073875	Abbexa	EUR 328.00 EUR 6397.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

Hexokinase-2 Protein (Recombinant)
20-abx073876	Abbexa	EUR 328.00 EUR 6397.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

Hexokinase-3 Protein (Recombinant)
20-abx073877	Abbexa	EUR 328.00 EUR 6397.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

Hexokinase-4 Protein (Recombinant)
20-abx073882	Abbexa	EUR 328.00 EUR 6397.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

Pyridoxal Kinase Protein (Recombinant)
20-abx073893	Abbexa	EUR 328.00 EUR 6397.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

Cyclin-B1 Protein (Recombinant)
20-abx073999	Abbexa	EUR 1609.00 EUR 328.00 EUR 230.00	100 ug 10 ug 2 µg
Shipped within 5-10 working days.

c-erbB2 Protein (Recombinant)
20-abx074013	Abbexa	EUR 829.00 EUR 411.00 EUR 537.00	10 ug 2 µg 5 ug
Shipped within 5-10 working days.

Pantothenate Kinase Protein (Recombinant)
20-abx076001	Abbexa	EUR 17798.00 EUR 10559.00 EUR 1080.00 EUR 704.00	100 mg 1 mg 20 ug 5 ug
Shipped within 3 months.

Recombinant Green Fluorescent Protein
7-06112	CHI Scientific	10µg	Ask for price

Recombinant Green Fluorescent Protein
7-06113	CHI Scientific	50µg	Ask for price

Recombinant Green Fluorescent Protein
7-06114	CHI Scientific	1mg	Ask for price

Recombinant Staphylococcal Protein-A
7-06496	CHI Scientific	10mg	Ask for price

Recombinant Staphylococcal Protein-A
7-06497	CHI Scientific	100mg	Ask for price

Recombinant Staphylococcal Protein-A
7-06498	CHI Scientific	1gram	Ask for price

Recombinant Der P1 Protein
7-07081	CHI Scientific	100µg	Ask for price

Recombinant Der P1 Protein
7-07082	CHI Scientific	500µg	Ask for price

Recombinant Der P1 Protein
7-07083	CHI Scientific	1000µg	Ask for price

Recombinant Der F1 Protein
7-07084	CHI Scientific	100µg	Ask for price

Recombinant Der F1 Protein
7-07085	CHI Scientific	500µg	Ask for price

Recombinant Der F1 Protein
7-07086	CHI Scientific	1000µg	Ask for price

Recombinant Malaria Protein HSP70
7-07087	CHI Scientific	100µg	Ask for price

Recombinant Malaria Protein HSP70
7-07088	CHI Scientific	500µg	Ask for price

Recombinant Malaria Protein HSP70
7-07089	CHI Scientific	1000µg	Ask for price

Recombinant LASA Z Protein
0508-001	IBT Bioservices	100ug	EUR 491
Description: Related to: Filoviruses Applications: ELISA, WB

Recombinant Protein A/G
7-05932	CHI Scientific	1mg	Ask for price

Recombinant Protein A/G
7-05933	CHI Scientific	10mg	Ask for price

Recombinant Protein A/G
7-05934	CHI Scientific	100mg	Ask for price

Recombinant Human ACE2 Protein
ACE2-185H-20ug	Creative-Biomart	20ug	EUR 570
Description: Recombinant human ACE2 (NP_068576.1) (Met1-Ser740) was expressed with the Fc region of mouse IgG1 at the C-terminus.

Recombinant Human ACE2 Protein
ACE2-185H-50ug	Creative-Biomart	50ug	EUR 830
Description: Recombinant human ACE2 (NP_068576.1) (Met1-Ser740) was expressed with the Fc region of mouse IgG1 at the C-terminus.

Schwann Cell Cultures: Biology, Expertise and Therapeutics

Schwann cell (SC) cultures from experimental animals and human donors will be ready utilizing almost any kind of nerve at any stage of maturation to render stage- and patient-specific populations. Strategies to isolate, purify, develop in quantity, and differentiate SCs from grownup, postnatal and embryonic sources are environment friendly and reproducible as these have resulted from amassed refinements launched over many a long time of labor. 

Albeit some exceptions, SCs will be passaged extensively whereas sustaining their regular proliferation and differentiation controls. Because of their lineage dedication and powerful resistance to tumorigenic transformation, SCs are secure to be used in therapeutic approaches within the peripheral and central nervous programs. 

This evaluate summarizes the evolution of labor that led to the strong applied sciences used at present in SC culturing together with the primary options of the first and expanded SCs that make them irreplaceable fashions to grasp SC biology in well being and illness. Conventional and rising approaches in SC tradition are mentioned in mild of their potential functions.  

Lastly, some fundamental assumptions in vitro SC fashions are recognized in an try and uncover the mixed worth of previous and new developments in tradition protocols and the mobile merchandise which might be derived.   

Atherosclerosis: cell biology and lipoproteins

Objective of evaluate: Lipoproteins have vital function in each the promotion and prevention of atherosclerosis. This transient evaluate will concentrate on latest stories on relationship between HDL and HDL subclasses and their composition and performance, the function of apoC-III in metabolism of triglyceride-rich lipoproteins, the affect of Lipoprotein (a) (Lp(a)) on endothelial cells, and the mechanism of uptake of aggregated LDL by macrophages.

Latest findings: The complexity of the protein and lipid content material of murine and human HDL and their relationship to its ldl cholesterol efflux capability have been examined. HDL has additionally been proven to have each antiatherogenic and proatherogenic properties. 

The connection between apoC-III and LPL exercise, apoprotein E mediated clearance of triglyceride-rich lipoproteins and the potential significance of apoC-III within the elevated threat of heart problems in kind 1 diabetics has been investigated. Oxidized phospholipid in Lp(a) promotes endothelial cells inflammatory and glycolytic responses.

TLR4 participates within the uptake of aggregated LDL to contribute to foam cell formation. Abstract: These research contribute to our mechanistic understanding of how lipoproteins contribute to atherogenesis and determine potential therapeutic targets. 

RLIM Antibody
1-CSB-PA019748GA01HU	Cusabio	EUR 597.00 EUR 333.00	150ul 50ul
Form: Liquid Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20℃, Avoid freeze / thaw cycles. Antigen Affinity purified
Description: A polyclonal antibody against RLIM. Recognizes RLIM from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB

Rabbit Polyclonal antibody Anti-CRBN
Anti-CRBN	ImmunoStep	50 µg	EUR 349

RLIM Polyclonal Antibody
29447-100ul	SAB	100ul	EUR 252

RLIM Polyclonal Antibody
29447-50ul	SAB	50ul	EUR 187

RLIM siRNA
20-abx931585	Abbexa	EUR 551.00 EUR 732.00	15 nmol 30 nmol
Shipped within 5-10 working days.

RLIM siRNA
20-abx931586	Abbexa	EUR 551.00 EUR 732.00	15 nmol 30 nmol
Shipped within 5-10 working days.

RLIM Polyclonal Conjugated Antibody
C29447	SAB	100ul	EUR 397

RLIM Rabbit pAb
A15837-100ul	Abclonal	100 ul	EUR 308

RLIM Rabbit pAb
A15837-200ul	Abclonal	200 ul	EUR 459

RLIM Rabbit pAb
A15837-20ul	Abclonal	20 ul	EUR 183

RLIM Rabbit pAb
A15837-50ul	Abclonal	50 ul	EUR 223

RLIM Blocking Peptide
DF12723-BP	Affbiotech	1mg	EUR 195

Mouse E3 ubiquitin- protein ligase RLIM, Rlim ELISA KIT
ELI-52811m	Lifescience Market	96 Tests	EUR 865

Human E3 ubiquitin- protein ligase RLIM, RLIM ELISA KIT
ELI-40904h	Lifescience Market	96 Tests	EUR 824

Polyclonal Goat anti-GST α-form
GST-ANTI-1	Detroit R&D	50 uL	EUR 280

Polyclonal Goat anti-GST μ-form
GST-ANTI-2	Detroit R&D	50 uL	EUR 280

Polyclonal Goat anti-GST p-form
GST-ANTI-3	Detroit R&D	50 uL	EUR 280

RLIM ELISA KIT|Human
EF002487	Lifescience Market	96 Tests	EUR 689

Human RLIM shRNA Plasmid
20-abx959551	Abbexa	EUR 801.00 EUR 1121.00	150 µg 300 µg
Shipped within 15-20 working days.

Mouse RLIM shRNA Plasmid
20-abx972467	Abbexa	EUR 801.00 EUR 1121.00	150 µg 300 µg
Shipped within 15-20 working days.

RLIM Recombinant Protein (Human)
RP026497	ABM	100 ug	Ask for price

RLIM Recombinant Protein (Rat)
RP226193	ABM	100 ug	Ask for price

RLIM Recombinant Protein (Mouse)
RP168323	ABM	100 ug	Ask for price

RLIM ORF Vector (Human) (pORF)
ORF008833	ABM	1.0 ug DNA	EUR 95

Rlim ORF Vector (Mouse) (pORF)
ORF056109	ABM	1.0 ug DNA	EUR 506

Rlim ORF Vector (Rat) (pORF)
ORF075399	ABM	1.0 ug DNA	EUR 506

Ring Finger Protein, Lim Domain Interacting (RLIM) Antibody
20-abx115301	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul
Shipped within 5-10 working days.

Ring Finger Protein, LIM Domain Interacting (RLIM) Antibody
abx237320-100ug	Abbexa	100 ug	EUR 509
Shipped within 5-12 working days.

RLIM sgRNA CRISPR Lentivector set (Human)
K1827101	ABM	3 x 1.0 ug	EUR 339

Rlim sgRNA CRISPR Lentivector set (Rat)
K6457601	ABM	3 x 1.0 ug	EUR 339

Rlim sgRNA CRISPR Lentivector set (Mouse)
K5023801	ABM	3 x 1.0 ug	EUR 339

RLIM sgRNA CRISPR Lentivector (Human) (Target 1)
K1827102	ABM	1.0 ug DNA	EUR 154

RLIM sgRNA CRISPR Lentivector (Human) (Target 2)
K1827103	ABM	1.0 ug DNA	EUR 154

RLIM sgRNA CRISPR Lentivector (Human) (Target 3)
K1827104	ABM	1.0 ug DNA	EUR 154

Rlim sgRNA CRISPR Lentivector (Rat) (Target 1)
K6457602	ABM	1.0 ug DNA	EUR 154

Rlim sgRNA CRISPR Lentivector (Rat) (Target 2)
K6457603	ABM	1.0 ug DNA	EUR 154

Rlim sgRNA CRISPR Lentivector (Rat) (Target 3)
K6457604	ABM	1.0 ug DNA	EUR 154

Rlim sgRNA CRISPR Lentivector (Mouse) (Target 1)
K5023802	ABM	1.0 ug DNA	EUR 154

Rlim sgRNA CRISPR Lentivector (Mouse) (Target 2)
K5023803	ABM	1.0 ug DNA	EUR 154

Rlim sgRNA CRISPR Lentivector (Mouse) (Target 3)
K5023804	ABM	1.0 ug DNA	EUR 154

RLIM Protein Vector (Human) (pPB-C-His)
PV035329	ABM	500 ng	EUR 329

RLIM Protein Vector (Human) (pPB-N-His)
PV035330	ABM	500 ng	EUR 329

RLIM Protein Vector (Human) (pPM-C-HA)
PV035331	ABM	500 ng	EUR 329

RLIM Protein Vector (Human) (pPM-C-His)
PV035332	ABM	500 ng	EUR 329

RLIM Protein Vector (Rat) (pPB-C-His)
PV301594	ABM	500 ng	EUR 603

RLIM Protein Vector (Rat) (pPB-N-His)
PV301595	ABM	500 ng	EUR 603

RLIM Protein Vector (Rat) (pPM-C-HA)
PV301596	ABM	500 ng	EUR 603

RLIM Protein Vector (Rat) (pPM-C-His)
PV301597	ABM	500 ng	EUR 603

RLIM Protein Vector (Mouse) (pPB-C-His)
PV224434	ABM	500 ng	EUR 603

RLIM Protein Vector (Mouse) (pPB-N-His)
PV224435	ABM	500 ng	EUR 603

RLIM Protein Vector (Mouse) (pPM-C-HA)
PV224436	ABM	500 ng	EUR 603

RLIM Protein Vector (Mouse) (pPM-C-His)
PV224437	ABM	500 ng	EUR 603

Rlim 3'UTR GFP Stable Cell Line
TU167914	ABM	1.0 ml	Ask for price

RLIM 3'UTR Luciferase Stable Cell Line
TU019947	ABM	1.0 ml	EUR 4617

Rlim 3'UTR Luciferase Stable Cell Line
TU117914	ABM	1.0 ml	Ask for price

RLIM 3'UTR GFP Stable Cell Line
TU069947	ABM	1.0 ml	EUR 4617

Rlim 3'UTR Luciferase Stable Cell Line
TU219467	ABM	1.0 ml	Ask for price

Rlim 3'UTR GFP Stable Cell Line
TU269467	ABM	1.0 ml	Ask for price

Human Ring Finger Protein, LIM Domain Interacting (RLIM) ELISA Kit
abx382827-96tests	Abbexa	96 tests	EUR 911
Shipped within 5-12 working days.

RLIM sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
K1827105	ABM	3 x 1.0 ug	EUR 376

Rlim sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)
K6457605	ABM	3 x 1.0 ug	EUR 376

Rlim sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
K5023805	ABM	3 x 1.0 ug	EUR 376

RLIM sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)
K1827106	ABM	1.0 ug DNA	EUR 167

RLIM sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)
K1827107	ABM	1.0 ug DNA	EUR 167

RLIM sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)
K1827108	ABM	1.0 ug DNA	EUR 167

Rlim sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)
K6457606	ABM	1.0 ug DNA	EUR 167

Rlim sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)
K6457607	ABM	1.0 ug DNA	EUR 167

Rlim sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)
K6457608	ABM	1.0 ug DNA	EUR 167

Rlim sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)
K5023806	ABM	1.0 ug DNA	EUR 167

Rlim sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)
K5023807	ABM	1.0 ug DNA	EUR 167

Rlim sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)
K5023808	ABM	1.0 ug DNA	EUR 167

Anti-Anti-SEPT2 Antibody antibody
STJ28365	St John's Laboratory	100 µl	EUR 277

Anti-Anti-SEPT7 Antibody antibody
STJ28963	St John's Laboratory	100 µl	EUR 277
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT6 antibody antibody
STJ11100949	St John's Laboratory	100 µl	EUR 277
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Anti-Anti-SEPT2 Antibody antibody
STJ25475	St John's Laboratory	100 µl	EUR 277

Anti-Anti-SEPT5 Antibody antibody
STJ25477	St John's Laboratory	100 µl	EUR 277
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-SEPT8 Antibody antibody
STJ25479	St John's Laboratory	100 µl	EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT9 Antibody antibody
STJ111369	St John's Laboratory	100 µl	EUR 277
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Anti-Anti-SEPT11 Antibody antibody
STJ111530	St John's Laboratory	100 µl	EUR 277

Anti-Anti-SEPT4 Antibody antibody
STJ112276	St John's Laboratory	100 µl	EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Anti-Anti-MARCH9 Antibody antibody
STJ112609	St John's Laboratory	100 µl	EUR 277

Anti-Anti-SEPT11 Antibody antibody
STJ113941	St John's Laboratory	100 µl	EUR 277

Anti-Anti-SEPT11 Antibody antibody
STJ114081	St John's Laboratory	100 µl	EUR 277

Anti-Anti-SEPT5 Antibody antibody
STJ114819	St John's Laboratory	100 µl	EUR 277
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-MARCH8 Antibody antibody
STJ114828	St John's Laboratory	100 µl	EUR 277

Anti-Anti-MARCH6 Antibody antibody
STJ118549	St John's Laboratory	100 µl	EUR 277

Anti-Anti-MARCH6 Antibody antibody
STJ118550	St John's Laboratory	100 µl	EUR 277

Anti-Anti-MARCH7 Antibody antibody
STJ118752	St John's Laboratory	100 µl	EUR 277

Anti-Anti-SEPT3 Antibody antibody
STJ118990	St John's Laboratory	100 µl	EUR 277

Anti-Anti-SEPT1 antibody antibody
STJ119580	St John's Laboratory	100 µl	EUR 277
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

Anti-Anti-SEPT7 Antibody antibody
STJ116214	St John's Laboratory	100 µl	EUR 277
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT8 Antibody antibody
STJ117206	St John's Laboratory	100 µl	EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT12 Antibody antibody
STJ117759	St John's Laboratory	100 µl	EUR 277
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.